Research programs in the Laboratory of Cancer Biology and Genetics (LCBG) are focused on human genetics, developing new cancer models, and investigating molecular mechanisms, including genetic/epigenetic regulation of gene expression, cell signaling, cell cycle, stemness, oncogene and non-oncogene addiction, and tumor cell-microenvironment interactions. Our goal is to understand the mechanisms underlying cancer initiation and metastatic progression and develop new treatments while nurturing the training and development of the next generation of scientists.