Search all CCR Clinical Trials
Below is a list of all open NCI Center for Cancer Research (CCR) clinical trials, including studies that are currently recruiting patients (i.e. Open - Recruiting) as well as trials that will be recruiting soon (i.e., Open - Not yet Recruiting). Most recently opened trials are listed first.
All CCR clinical trials take place at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.
Clinical trials at the NIH Clinical Center are open to patients with cancer, HIV, or immunodeficiency disorders, regardless of where they live in the United States.
-
A Phase I/II Study of the Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Advanced Pancreas Cancer.
Open - Not yet Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-20-C-0074Investigator Udo Rudloff, M.D., Ph.D. -
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Primary Immunodeficiency Diseases
Open - Not yet Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-20-C-0070Investigator Dennis D. Hickstein, M.D. -
Phase 2 Trial of Encorafenib plus Binimetinib for patients with BRAF V600E mutated relapsed/refractory HCL
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0076Investigator Robert J. Kreitman, M.D. -
Phase 2 Trial for Binimetinib for Patients with Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0075Investigator Robert J. Kreitman, M.D. -
A Phase II Pilot Trial to Estimate Survival After A Non-Total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed with B-Acute Lymphoblastic Leukemia (ALL) Who are Pre-Allogeneic Hematopoietic Cell Transplantation (HCT)
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0042Investigator Haneen Shalabi, D.O.Share this trial: Referral ContactsContact Name Phone Number NCI Pediatric Leukemia Lymphoma BMT Team (240) 760-6970 -
Phase I/II of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi Sarcoma
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0061Investigator Ramya Ramaswami, M.B.B.S., M.P.H. -
A Phase II Feasibility Trial Using Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0065Investigator Terri S. Armstrong, Ph.D., ANP-BC, FAAN, FAANP -
Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia
Open - RecruitingNCI Protocol ID NCI-20-C-0028Investigator Nirali N. Shah, M.D., M.H.Sc.Share this trial: Referral ContactsContact Name Phone Number NCI Pediatric Leukemia Lymphoma BMT Team (240)760-6970 -
A Phase 1b Trial of Sequential Combinations of BN-Brachyury, Entinostat, ado-trastuzuamb emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0056Investigator Margaret E. Gatti-Mays, M.D., M.P.H., F.A.C.P. -
Phase I/II Trial of Combination Immunotherapy in Subjects with Advanced HPV Associated Malignancies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0045Investigator Julius Strauss, M.D. -
A Study of front line Ibrutinib for Newly Diagnosed Chronic Graft-versus-Host Disease
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0058Investigator Steven Z. Pavletic, M.D., M.S.Share this trial: Referral ContactsContact Name Phone Number -
A Phase 1, First-in-Human, Dose Escalation Study of JNJ-63898081 in Subjects with Advanced Stage Solid Tumors
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0015Investigator James L. Gulley, M.D., Ph.D.Share this trial: Referral ContactsContact Name Phone Number -
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Experimental Transplantation and Immunotherapy Branch Studies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0051Investigator Christian S. Hinrichs, M.D. -
THREAD: A Phase I Trial of Trametinib and Hydroxychloroquine in Patients with Advanced Pancreatic Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0043Investigator Christine Campo Alewine, M.D., Ph.D. -
A Sequential Window of Opportunity Trial of Anti-PD-L1/TGF-ß trap (M7824 ) Alone and in Combination with TriAd Vaccine, and N-803 for p16-Negative Resectable Head and Neck Squamous Cell Carcinoma
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0024Investigator Jason M. Redman, M.D. -
A Phase I study of TGF-ß trap (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary Malignancies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0012Investigator Andrea B. Apolo, M.D. -
First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid Tumors
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0023Investigator Udo Rudloff, M.D., Ph.D.Share this trial: Referral ContactsContact Name Phone Number -
A Phase 1/2 open-label, multi-center, dose-escalation study of safety, tolerability, pharmacokinetics, dosimetry, and response to repeat dosing of 177Lu-PSMA-R2 radio-ligand therapy in patients with prostate specific membrane antigen (PSMA) positive
Open - RecruitingNCI Protocol ID NCI-20-C-0035Investigator Frank I. Lin, M.D. -
Ex-Vivo Trial of En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device
Open - RecruitingNCI Protocol ID NCI-20-C-0020Investigator Vladimir A. Valera Romero M.D., Ph.D. -
Radium-223 in Biochemically Recurrent Prostate Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0010Investigator Ravi A. Madan, M.D.Share this trial: Referral ContactsContact Name Phone Number Anna Couvillon 240-858-3148 Ravi Madan 301-480-7168