All Open Clinical Trials
Below is a list of all open NCI Center for Cancer Research (CCR) clinical trials, including studies that are currently recruiting patients (i.e. Open - Recruiting) as well as trials that will be recruiting soon (i.e., Open - Not yet Recruiting). Most recently opened trials are listed first.
All CCR clinical trials take place at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.
Clinical trials at the NIH Clinical Center are open to patients with cancer, HIV, or immunodeficiency disorders, regardless of where they live in the United States.
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A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following Chemotherapy
Open - Not yet Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-19-C-0134Investigator Ronald E. Gress, M.D. -
Natural history and evaluation of abnormal and nonreportable noninvasive prenatal testing NIPT results and its association with maternal neoplasia
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0132Investigator Christina M. Annunziata, M.D., Ph.D. -
Development and Psychometric Testing of a Pediatric Chronic Graft- Versus-Host Disease (GVHD) Symptom Scale (PCSS)
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0131Investigator Lori Wiener, Ph.D., DCSW, LCSW-C -
Development and Psychometric Testing of a Pediatric Chronic GVHD Symptom Scale (PCSS)
Open - Not yet Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-19-C-0121Investigator Lori Wiener, Ph.D., DCSW, LCSW-C -
A Phase II study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0130Investigator Christian S. Hinrichs, M.D. -
A Phase II Study of Intraperitoneal and Intravenous Paclitaxel Chemotherapy with Oral Capecitabine for Gastric Adenocarcinoma with Peritoneal Carcinomatosis
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0129Investigator Jeremy L. Davis, M.D. -
A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid Tumors
Open - RecruitingNCI Protocol ID NCI-19-C-0128Investigator Christine Campo Alewine, M.D., Ph.D. -
A Phase II Study of LMB-100 Followed by Pembrolizumab in the Treatment of Adults with Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0127Investigator Azam Ghafoor, M.D.Share this trial: Referral ContactsContact Name Phone Number -
Phase II Study of Oral Vancomycin in Patients with Unresectable Fibrolamellar Hepatocellular Carcinoma (FLC)
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0125Investigator Tim F. Greten, M.D. -
A Phase II Study of E7 TCR T Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0122Investigator Christian S. Hinrichs, M.D. -
An Open-Label, Multicenter Rollover Study to Provide Continued Treatment with Anetumab Ravtansine For Participants with Solid Tumors Who Were Enrolled in Previous Bayer-Sponsored Studies.
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0119Investigator Raffit Hassan, M.D. -
A Phase 1 / 2 Single Arm Open-label Clinical Trial of TC-210 T-Cells in Patients with Advanced Mesothelin Expressing Cancer
Open - RecruitingNCI Protocol ID NCI-19-C-0117Investigator Raffit Hassan, M.D. -
A Phase 2 Study of Acalabrutinib with DA-EPOCH-R or R-CHOP for Patients with Untreated Diffuse Large B-cell Lymphoma
Open - RecruitingNCI Protocol ID NCI-19-C-0116Investigator Mark Roschewski, M.D. -
Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic Malignancies
Open - RecruitingNCI Protocol ID NCI-19-C-0112Investigator Christopher G. Kanakry, M.D. -
A Phase II Multi-Institutional Trial to Evaluate Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0104Investigator William L. Dahut, M.D. -
A Study of Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas with Secondary Involvement of the Central Nervous System (CNS)
Open - RecruitingNCI Protocol ID NCI-19-C-0103Investigator Mark Roschewski, M.D. -
A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple Myeloma
Open - RecruitingNCI Protocol ID NCI-19-C-0102Investigator James N. Kochenderfer, M.D. -
Studying the biology of IDH-mutant gliomas via longitudinal observation of 2-hydroxyglutarate (2-HG) using MR spectroscopy
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0096Investigator Jing Wu, M.D., Ph.D.Share this trial: Referral ContactsContact Name Phone Number Ann McCoy 240-760-6021 Christine Bryla 240-760-6007 -
A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC)
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0094Investigator Tim F. Greten, M.D. -
A Phase II Study of Immunotherapy with E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Open - RecruitingNCI Protocol ID NCI-19-C-0091Investigator Christian S. Hinrichs, M.D.