Search all CCR Clinical Trials
Below is a list of all open NCI Center for Cancer Research (CCR) clinical trials, including studies that are currently recruiting patients (i.e. Open - Recruiting) as well as trials that will be recruiting soon (i.e., Open - Not yet Recruiting). Most recently opened trials are listed first.
All CCR clinical trials take place at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.
Clinical trials at the NIH Clinical Center are open to patients with cancer, HIV, or immunodeficiency disorders, regardless of where they live in the United States.
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A Phase 2 Randomized Study of the Efficacy and Safety of Acalabrutinib with Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized with COVID-19
Open - Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-20-C-0133Investigator Mark Roschewski, M.D. -
A Pilot Study of E7 TCR T Cell Induction Immunotherapy for Stage IIB-IVA Cervical Cancer
Open - Not yet Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-20-C-0116Investigator Christian S. Hinrichs, M.D. -
Natural History Study of Children and Adults with Neuroendocrine Neoplasms (NEN)s
Open - Recruiting Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-20-C-0139Investigator Jaydira Del Rivero, M.D. -
A Phase 1 Study of Romidepsin, 5-azacitidine, dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignancies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0127Investigator Milos Miljković, M.D., M.Sc. -
Natural History Study of Children and Adults with Adrenocortical Cancer
Open - RecruitingNCI Protocol ID NCI-20-C-0110Investigator Jaydira Del Rivero, M.D. -
A Feasibility Study Investigating the Use of Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer Pain
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0130Investigator James L. Gulley, M.D., Ph.D.Share this trial: Referral ContactsContact Name Phone Number -
Prospective Evaluation of High Resolution Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition Syndrome#xD;
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0106Investigator David S. Schrump, M.D., M.B.A. -
Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination with Anti-PD-L1/TGF-ß trap (M7824) in Subjects with HPV Positive Cancers
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0104Investigator Julius Strauss, M.D.Share this trial: Referral ContactsContact Name Phone Number -
Biospecimen Procurement for Immunological Landscape Studies Following Hematopoietic Cell Transplantation
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0072Investigator Christian S. Hinrichs, M.D. -
A Phase II, Open-Label Trial of Bintrafusp Alfa (M7824) in Subjects with Thymoma and Thymic Carcinoma
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0097Investigator Arun Rajan, M.D.Share this trial: Referral ContactsContact Name Phone Number -
A Phase I Study of E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial Neoplasia
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0093Investigator Christian S. Hinrichs, M.D. -
Investigation of the B- and T-cell repertoire and immune response in patients with acute and resolved COVID-19 infection
Open - RecruitingNCI Protocol ID NCI-20-C-0103Investigator Robert J. Kreitman, M.D. -
A Phase I/II Study of the Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Advanced Pancreas Cancer.
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0074Investigator Udo Rudloff, M.D., Ph.D. -
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Primary Immunodeficiency Diseases
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0070Investigator Dennis D. Hickstein, M.D. -
Phase 2 Trial of Encorafenib plus Binimetinib for patients with BRAF V600E mutated relapsed/refractory HCL
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0076Investigator Robert J. Kreitman, M.D. -
Phase 2 Trial for Binimetinib for Patients with Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0075Investigator Robert J. Kreitman, M.D. -
A Phase II Pilot Trial to Estimate Survival After A Non-Total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed with B-Acute Lymphoblastic Leukemia (ALL) Who are Pre-Allogeneic Hematopoietic Cell Transplantation (HCT)
Open - RecruitingNCI Protocol ID NCI-20-C-0042Investigator Haneen Shalabi, D.O.Share this trial: Referral ContactsContact Name Phone Number NCI Pediatric Leukemia Lymphoma BMT Team (240) 760-6970 -
Phase I/II of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi Sarcoma
Open - RecruitingNCI Protocol ID NCI-20-C-0061Investigator Ramya Ramaswami, M.B.B.S., M.P.H. -
A Phase II Feasibility Trial Using Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0065Investigator Terri S. Armstrong, Ph.D., ANP-BC, FAAN, FAANP -
Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia
Open - RecruitingNCI Protocol ID NCI-20-C-0028Investigator Nirali N. Shah, M.D., M.H.Sc.Share this trial: Referral ContactsContact Name Phone Number NCI Pediatric Leukemia Lymphoma BMT Team (240)760-6970