All Open Clinical Trials
Below is a list of all open NCI Center for Cancer Research (CCR) clinical trials, including studies that are currently recruiting patients (i.e. Open - Recruiting) as well as trials that will be recruiting soon (i.e., Open - Not yet Recruiting). Most recently opened trials are listed first.
All CCR clinical trials take place at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.
Clinical trials at the NIH Clinical Center are open to patients with cancer, HIV, or immunodeficiency disorders, regardless of where they live in the United States.
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A Phase 2 Study of Response-Adapted Therapy with Copanlisib and Rituximab in Untreated Follicular Lymphoma #xD;
Open - Not yet Recruiting Protocol Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-19-C-0030Investigator Mark Roschewski, M.D. -
Tissue Acquisition and Genomics Analysis of Breast and Other Gynecologic Malignancies
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0025Investigator Christina M. Annunziata, M.D., Ph.D. -
A Phase II Study of Olaparib in Patients with Metastatic/Advanced Urothelial Carcinoma with DNA-Repair Defects
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0023Investigator Andrea B. Apolo, M.D. -
Phase 1 Trial of Human IL-15 (rhIL-15) and Obinutuzumab for Relapsed and Refractory Chronic Lymphocyte Leukemia
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0024Investigator Milos Miljković, M.D., M.Sc. -
A Natural History Study of Children and Adults with Fibrolamellar Hepatocellular Carcinoma
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0021Investigator Tim F. Greten, M.D. -
A Randomized Phase 2 Trial of Durvalumab (MEDI4736) with or without SBRT in Clinical Stage I, II, and IIIA Non-Small Cell Lung Cancer (NSCLC)
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0018Investigator David S. Schrump, M.D., M.B.A. -
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Open - RecruitingNCI Protocol ID NCI-19-C-0017Investigator James C. Yang, M.D.Share this trial: Referral ContactsContact Name Phone Number Immunotherapy Recruitment Center 866-820-4505 -
Natural History and Biospecimen Accrual Study for Children and Adults with Rare Solid Tumors
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0016Investigator Jaydira Del Rivero, M.D. -
Phase II Clinical Trial of Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0011Investigator Mark R. Gilbert, M.D.Share this trial: Referral ContactsContact Name Phone Number Ann McCoy 240-760-6021 Christine Bryla 240-760-6007 -
Phase II trial evaluating Nivolumab in patients with IDH-mutant gliomas with and without hypermutator phenotype
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0006Investigator Jing Wu, M.D., Ph.D. -
A Phase II Study of M7824 in Subjects with Recurrent Respiratory Papillomatosis
Open - RecruitingNCI Protocol ID NCI-19-C-0002Investigator Christian S. Hinrichs, M.D. -
Phase 1 with Expansion Cohorts in a Study of NEO-201 In Adults with Chemo-resistant Solid Tumors
Open - RecruitingNCI Protocol ID NCI-18-C-0147Investigator Christina M. Annunziata, M.D., Ph.D. -
A Phase 1 Study of Intraperitoneal MCY-M11 Therapy for Women with Platinum Resistant High Grade Serous Adenocarcinoma of the Ovary, Primary Peritoneum, or Fallopian Tube, or Subjects with Peritoneal Mesothelioma with Recurrence after Prior
Open - RecruitingNCI Protocol ID NCI-18-C-0143Investigator Christina M. Annunziata, M.D., Ph.D. -
Exploring Outcomes and Risk in Patients with Rare Central Nervous System Tumors
Open - RecruitingNCI Protocol ID 17-C-N141Investigator Terri S. Armstrong, Ph.D., ANP-BC, FAAN, FAANP -
An Open-Label Phase 2 Study to Evaluate PT2977 for the Treatment of Von Hippel-Lindau Disease-Associated Renal Cell Carcinoma.
Open - RecruitingNCI Protocol ID NCI-18-C-0138Investigator Ramaprasad Srinivasan, M.D., Ph.D. -
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Open - RecruitingNCI Protocol ID NCI-18-C-0135Investigator Jennifer A. Kanakry, M.D. -
Phase II Study of the Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma
Open - RecruitingNCI Protocol ID NCI-18-C-0136Investigator Raffit Hassan, M.D. -
Phase II Study Evaluating Confocal Endoscopic Microscopy for Detection of Early Stage Gastric Cancer in Subjects with Hereditary Diffuse Gastric Cancer Syndrome
Open - Not yet RecruitingNCI Protocol ID NCI-18-C-0141Investigator Jeremy L. Davis, M.D. -
Phase II clinical trial of sunitinib in sarcomas of the central nervous system
Open - Not yet RecruitingNCI Protocol ID NCI-18-C-0137Investigator Mark R. Gilbert, M.D. -
PRISM: A Platform protocol for the Treatment of Relapsed/Refractory Aggressive Non-Hodgkinamp;#39;s Lymphoma
Open - RecruitingNCI Protocol ID NCI-18-C-0130Investigator Mark Roschewski, M.D.