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Faculty News

Elaine Jaffe and Ira Pastan elected as 2025 Fellows of the AACR Academy

Elaine S. Jaffe, M.D., NIH Distinguished Investigator in the Laboratory of Pathology, and Ira Pastan, M.D., Chief Emeritus of the Laboratory of Molecular Biology, were elected in the 2025 class of Fellows of the American Association for Cancer Research (AACR) Academy. The mission of the Academy is to recognize and honor extraordinary scientists whose groundbreaking contributions have driven significant innovation and progress in the fight against cancer. Jaffe is being recognized for her revolutionary research efforts in hematopathology and transforming diagnostic standards and care for lymphoma and leukemia; Pastan is being recognized for his visionary contributions to cancer therapy and the field of receptor biology. 

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Natasha Caplen appointed to Senior Investigator at CCR

The CCR community congratulates Natasha J. Caplen, Ph.D., who has been appointed Senior Investigator in the Genetics Branch. Caplen contributed to the discovery of RNA interference (RNAi) in mammalian cells and has pioneered approaches for exploiting this gene regulatory mechanism to investigate cancer biology and treatment. Her current studies focus on the functional genetic analysis of cancers driven by fusion oncogenes, particularly the pediatric tumor Ewing sarcoma.

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Nirali Shah elected to the American Society for Clinical Investigation

Nirali N. Shah, M.D., M.H.Sc., Lasker Clinical Research Scholar in the Pediatric Oncology Branch, was elected as a member of the American Society for Clinical Investigation (ASCI). The organization seeks to support the scientific efforts, educational needs, and clinical aspirations of physician-scientists to improve the health of all people. The 2025 newly elected members came from 46 different institutions and represent excellence across the breadth of academic medicine. 

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Chuan Wu appointed to Senior Investigator at CCR

The CCR community congratulates Chuan Wu, M.D., Ph.D., who has been appointed Senior Investigator in the Experimental Immunology Branch. Wu studies the role of intestinal neuroimmune interactions in health and disease. His lab works to understand the cellular and molecular mechanisms of the dynamic interplay between the enteric nervous system and the immune system to build a comprehensive view of intestinal homeostasis and to discover new therapeutics for intestinal inflammatory diseases.

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Daniel Larson appointed Chief of the Laboratory of Receptor Biology and Gene Expression

The CCR community congratulates Daniel R. Larson, Ph.D., who has been appointed Chief of the Laboratory of Receptor Biology and Gene Expression. Larson’s laboratory’s goal is to understand gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue. His current work is focused on applying experimental and theoretical approaches to the study of hematopoiesis in health and disease through the trans-NIH Myeloid Malignancies Program.

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Chengkai Dai appointed to Senior Investigator at CCR

The CCR community congratulates Chengkai Dai, Ph.D., who has been appointed Senior Investigator in the Mouse Cancer Genetics Program. Dai’s laboratory is a pioneer in the field of proteomic instability of cancer. His ongoing research focuses on the molecular mechanisms through which proteomic instability may affect genomic stability, cell invasion and autophagy, areas which hold promise to unveil new molecular pathways that could be targeted in cancer therapy.

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