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News and Events

Celebrating CCR Careers: Stefan Ambs, Ph.D., M.P.H.

Stefan Ambs, Ph.D., M.P.H., is a molecular epidemiologist whose expertise is in prostate and breast cancer with a focus on cancer health disparities and risk factors that alter the tumor microenvironment. After almost 25 years at the NCI, he retired in May 2025.

Clinical trial researching immunotherapy for head and neck cancer

A clinical trial led by Charalampos Floudas, M.D., D.M.Sc., M.S., Associate Research Physician in the Center for Immuno-Oncology, is researching a combination immunotherapy for adults with head and neck squamous cell carcinoma.

Headshots of Dr. Jiang, Dr. Shah, and Dr. Zhang

Three CCR researchers appointed as Senior Investigators

The CCR community congratulates Peng Jiang, Ph.D., Nirali N. Shah, M.D., M.H.Sc., and Ping Zhang, Ph.D., for recently being appointed as Senior Investigators in their respective labs and branches.

Clinical trial researching CAR T-cell therapy for rhabdomyosarcoma

A clinical trial led by Srivandana Akshintala, M.B.B.S., M.P.H., Assistant Research Physician in the Pediatric Oncology Branch, is researching CAR T-cell therapy for children and young adults with rhabdomyosarcoma.

Clinical trial researching drug therapy for solid tumors

A clinical trial led by Hoyoung M. Maeng, M.D., Associate Research Physician in the Center for Immuno-Oncology, is researching a drug therapy for adults with advanced solid tumors.

Patient Testimonials

Read testimonials from patients and their families about their time at CCR.

Spatial heatmap of CD3+ T cells in small cell lung cancer (SCLC) tumors. Top: Notch1 gene inactive, “cold” SCLC with T cells located on the tumor periphery (immune-excluded). Bottom: Notch1 gene active, “hot” SCLC with abundant T cell tumor infiltration (immune-inflamed).

Activated gene elicits robust immune response in lung cancer

The activation of NOTCH1, a gene known to control cell differentiation and growth, stimulates a robust immune response in small cell lung cancer. Expression of this gene can also predict survival with immunotherapy.

Cells showing the biosensor used in this study to test the activity of APC/C

Study uncovers new details on pulsing enzyme activity during cell cycle

Enzymatic activity during the start of the cell cycle could be harnessed to inhibit cancer cell reproduction.

An illustration of immune cells with zeroes and ones, representing CIDE, a new, large-scale immuno-oncology data platform.

Cancer Immunology Data Engine uncovers secreted proteins with therapeutic potential

CCR researchers have developed a new tool that identifies secreted proteins associated with immunotherapy outcomes.

Graphic depiction of near-infrared photoimmunotherapy (NIR-PIT) targeted against ICAM-1 markers (small, blue, Y-shaped), causing cancer cell death and suppressed tumor growth (pink cluster, center).

CCR-developed cancer therapy shrinks tumors and boosts immune response

A targeted cancer therapy developed at CCR shows promise in its ability to target a common cancer cell marker, both shrinking tumors and producing a boosted immune response.

Clinical trial researching drug therapy for colorectal cancer

A clinical trial led by Tim F. Greten, M.D., Deputy Chief and Senior Investigator in the Thoracic and GI Malignancies Branch, is researching a two-drug therapy for adults with metastatic colorectal cancer.

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News and Events