Clinical trial studies combination therapy for B-cell lymphoma that has spread to the central nervous system
Mark Roschewski, M.D., Senior Clinician in the Lymphoid Malignancies Branch, is leading a study of a combination therapy to treat aggressive B-cell lymphoma that has spread to the brain and spinal cord. Read more...
Clinical trial tests chemotherapy dose for graft-versus-host disease after bone marrow transplant
Oct 11, 2019
The use of cyclophosphamide after hematopoietic cell transplantation (post-transplantation cyclophosphamide) may reduce the risk of severe forms of graft-versus-host disease (GVHD), particularly chronic GVHD. Christopher G. Kanakry, M.D., Investigator in the Experimental Transplantation and Immunology Branch, is conducting a clinical trial to test if an intermediate dose of this drug is better than higher doses as well as evaluating the optimal time to give this drug. Read more...
Tim Greten discusses liver cancer with OncLive
Oct 7, 2019
Tim Greten, M.D., Deputy Chief of the Thoracic and GI Malignancies Branch, was recently interviewed by OncLive. In the interview, Dr. Greten discussed the role of the gut microbiome in antitumor immunity in liver cancer. Read more...
Amy LeBlanc discusses how dogs are helping cure childhood cancers
Oct 7, 2019
Amy LeBlanc, D.V.M., Director of the Center for Cancer Research’s Comparative Oncology Program, was recently featured in an Everyday Health article that discusses the importance of studying the connection between cancer in dogs and cancer in children. Dr. LeBlanc says, “By studying [dogs] in the context of clinical trials, it can advance new concepts and better treatment for humans and, potentially, for dogs as patients themselves.” Read more...
Diversity of liver cancer cells can impede tumors’ response to immunotherapy
Oct 3, 2019
New research from the NCI’s Center for Cancer Research shows that understanding the impacts of cellular diversity on liver tumors’ microenvironment suggests ways to make immunotherapy effective for more patients. Read more...
Steve Rosenberg receives Friends of Cancer Research Cancer Leadership Award
Oct 2, 2019
Steve Rosenberg, M.D., Ph.D., Chief of the Surgery Branch, recently received the Friends of Cancer Research Cancer Leadership Award. The award recognizes individuals who have been champions for cancer research and steadfast advocates for patients. Read more...
Breast Cancer Research
Oct 1, 2019
To recognize Breast Cancer Awareness Month this October, we are highlighting our researchers who are making discoveries in this field. Read more…
Lawrence Samelson receives Cancer Research Institute Coley Award
Sep 30, 2019
Lawrence Samelson, M.D., Chief of the Laboratory of Cellular and Molecular Biology, was named a recipient of the Cancer Research Institute’s 2019 William B. Coley Award for Distinguished Research in Basic and Tumor Immunology. The award recognizes scientists for their seminal discoveries in the fields of basic and tumor immunology. Read more...
Marston Linehan discusses kidney cancer breakthroughs with the Federal News Network podcast
Sep 30, 2019
Marston Linehan, M.D., Chief of the Urologic Oncology Branch, was recently featured on the Federal News Network podcast. During the episode, Dr. Linehan discussed how kidney cancer is not a single disease but rather a number of different cancers that all happen to occur in the kidney. He also discussed how human genetics research has led to advances in kidney cancer, such as discovering that there are multiple genes that cause 17 types of kidney cancer. He says that while there has been much progress, much work is still left to do. Read more...
The New York Times highlights the importance of physician-scientists
Sep 27, 2019
The New York Times recently posted an editorial highlighting the importance of physician-scientists in the medical field. The article cited several examples of discoveries made by physician-scientists that have changed the history of medicine, including the development of the HPV vaccine by Doug Lowy, M.D., Chief of the Laboratory of Cellular Oncology (LCO), and John Schiller, Ph.D., Deputy Chief of LCO. Read more...
Advanced imaging technology reveals pulsed hormone release regulates gene transcription
Sep 19, 2019
Using advanced microscopic imaging technology, CCR investigators have correlated a pulsed pattern of hormone release with bursts of transcription, the process in which the genetic information encoded by DNA is written into RNA. They are the first researchers to observe this process at a gene-specific level. Read more...