Research Section Overview

The Center for Cancer Research (CCR) is the basic and clinical intramural research program of the National Cancer Institute (NCI). CCR is a distinctive community of scientists and clinicians who integrate basic research discovery with the development of novel interventions against cancer and HIV/AIDS.

CCR investigators conduct high-risk, high-impact research; studies that require the type of long-term, sustained support that may not be possible elsewhere. Discoveries at the CCR have advanced our understanding of the biology of cancer and other diseases; many have been translated into new diagnostics and treatments for patients.

CCR's Research Program

  • Provides a highly interactive, multidisciplinary culture for basic and clinical researchers
  • Accelerates the translation of new discoveries from the laboratory to the clinic
  • Supports the study of rare cancers and underserved patient populations
  • Responds quickly to urgent public health needs, new goals, and new opportunities
  • Invests in the development of new technology and approaches
  • Promotes collaborations within NIH as well as partnerships with private industry and academia
  • Is committed to training the next generation of scientific leaders

NCI Centers of Excellence

Centers of Excellence serve to support the CCR’s dedication to long-term, high-risk, basic and clinical research in our areas of greatest strength:

NCI Faculties/Working Groups

Basic, clinical, and epidemiological researchers are working together with a common interest in a particular scientific discipline, disease, or approach. The intramural faculties and working groups have expanded and enhanced collaborations, interdisciplinary research, and translational (bench-to-clinic) science at the Institute. In addition, some groups include members from other NIH institutes as well as the extramural research community such as academia and NCI Cancer Centers.Learn more . . .

Special Initiatives and Programs

CCR has established several programs to address specific areas of cancer research:

Rare Diseases – This program focuses on rare cancers and diseases as well cancers that may be predominant in medically underserved populations.

Center for Advanced Preclinical Research (CAPR) – This center conducts comprehensive preclinical testing of early-stage candidate drugs. 

Center for Molecular Microscopy (CMM) – This center is developing new techniques and technologies for high resolution imaging by electron microscopy in 3D.

Comparative Oncology Program (COP) – This program helps researchers gain a better understanding the biology of cancer and improve the assessment of novel treatments for humans by treating pet animals with naturally occurring cancers.