News and Events
Celebrating CCR Careers: Alan Rein, Ph.D.
Alan Rein, Ph.D., is a known expert in the field of viral assembly, particularly in retroviruses like the human immunodeficiency virus (HIV). After an extensive career studying molecular mechanisms of retroviral replication and pathogenesis, he has announced his retirement.
Read MoreNIH study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry
CCR researchers led by Stefan Ambs, Ph.D., M.P.H., Senior Investigator in the Laboratory of Human Carcinogenesis, found that West African genetic ancestry was associated with increased prostate cancer among men living in disadvantaged neighborhoods but not among men living in more affluent neighborhoods. The findings suggest that neighborhood environment may play a role in determining how genetic ancestry influences prostate cancer risk.
Read MoreOpting for a Novel Combination Treatment for Resistant Aggressive B-Cell Lymphoma
In 2020, Justin enrolled in a CCR trial testing a five-drug combination treatment called ViPOR for non-Hodgkin lymphoma. Four years later, his doctor Christopher J. Melani, M.D., Assistant Research Physician in the Lymphoid Malignancies Branch, describes Justin as likely cancer-free.
Read MoreDaniel Larson appointed Chief of the Laboratory of Receptor Biology and Gene Expression
The CCR community congratulates Daniel R. Larson, Ph.D., who has been appointed Chief of the Laboratory of Receptor Biology and Gene Expression. Larson’s laboratory’s goal is to understand gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue. His current work is focused on applying experimental and theoretical approaches to the study of hematopoiesis in health and disease through the trans-NIH Myeloid Malignancies Program.
Read MoreClinical trial researching immunotherapy for solid tumors
A clinical trial led by Kevin C. Conlon, M.D., Associate Research Physician in the Women’s Malignancies Branch, is researching immunotherapy for solid tumors.
Read MoreClinical trial researching drug therapy for central nervous system tumors
A clinical trial led by Marta Penas-Prado, M.D., M.Sc., Senior Clinician in the Neuro-Oncology Branch, is researching drug therapy for tumors of the central nervous system.
Read MoreUnderstanding the Risk of Second Cancers After CAR T-Cell Therapy
Two recent reports in the New England Journal of Medicine are seeking to determine if there may be a causal link between CAR T-cell treatment and second cancers. In this Q&A, Stephanie L. Goff, M.D., Senior Research Physician in the Surgery Branch, discusses the findings and what this issue may mean in general for patients and this area of research.
Read MoreClinical trial researching immunotherapy for throat cancer
A clinical trial led by Clint T. Allen, M.D., Senior Investigator in the Surgical Oncology Program, is researching combination immunotherapy for HPV-associated throat cancer.
Read More2025 NCI RNA Biology Symposium
Date: April 3-4, 2025
Location: Building 45, Natcher Auditorium
The mission of the NCI RNA Biology Initiative is to create an interdisciplinary environment that promotes the swift exchange of information and expertise regarding the structure, function, and biological significance of RNA. Our objective is to leverage our collective knowledge to advance the development of novel diagnostics and therapies. This biennial symposium, organized by the NCI RNA Biology Initiative, offers the opportunity to learn about new advances in multiple areas of RNA biology, to share research and to network with leading scientists, and to discuss the use and implications of these advances for clinical medicine.
Read MoreClinical trial researching CAR T-cell therapy for certain large B-cell lymphomas
A clinical trial led by Nirali N. Shah, M.D., M.H.Sc., Lasker Clinical Research Scholar in the Pediatric Oncology Branch, is studying the use of CAR T-cell therapy for relapsed or refractory large B-cell lymphoma (LBCL).
Read MoreClinical trial researching immunotherapy for cervical cancer
A clinical trial led by James L. Gulley, M.D., Ph.D., Co-Director of the Center for Immuno-Oncology, is researching combination immunotherapy for cervical cancer.
Read More