Rosa Nguyen

Rosa Nguyen, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Pediatric Oncology Branch


Dr. Nguyen is a pediatric oncologist and physician-scientist specializing in the discovery and preclinical development of immunotherapies for the treatment of children with neuroblastoma. She earned her M.D. from the University of Hamburg, Germany, and completed her pediatric residency at the University of Maryland and her pediatric hematology-oncology fellowship training at St. Jude Children’s Research Hospital. Subsequently, she obtained her Ph.D. under the mentorship of Dr. Michael A. Dyer, studying natural killer cells and their therapeutic role in pediatric cancer.

Areas of Expertise

Information for Patients

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Selected Recent Publications

Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma

Ming Sun, Yingying Cao, Reona Okada, Jeyshka M Reyes-González, Hannah G Stack, Haiying Qin, Nan Li, Charlie Seibert, Michael C Kelly, Eytan Ruppin, Mitchell Ho, Carol J Thiele, Rosa Nguyen
J Immunother Cancer. 11/1: 2023.
Full-Text Article
[ Journal Article ]

Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma

Rosa Nguyen, Xiyuan Zhang, Ming Sun, Shahroze Abbas, Charlie Seibert, Michael C Kelly, Jack F Shern, Carol J Thiele
Clin Cancer Res. 28/17: 3785-3796, 2022.
Full-Text Article
[ Journal Article ]

Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial

Nguyen R, Sahr N, Sykes A, McCarville MB, Federico SM, Sooter A, Cullins D, Rooney B, Janssen WE, Talleur AC, Triplett BM, Anthony G, Dyer MA, Pappo AS, Leung WH, Furman WL.
J Immunother Cancer.. Mar;8(1):: e000176, 2020. [ Journal Article ]

Interleukin-15 Enhances Anti-GD2 Antibody-Mediated Cytotoxicity in an Orthotopic PDX Model of Neuroblastoma

Nguyen R, Moustaki A, Norrie JL, Brown S, Akers WJ, Shirinifard A, Dyer MA.
Clin Cancer Res. . Dec 15;25(24): 7554-7564, 2019. [ Journal Article ]

A phase II clinical trial of adoptive transfer of haploidentical natural killer cells for consolidation therapy of pediatric acute myeloid leukemia

Nguyen R, Wu H, Pounds S, Inaba H, Ribeiro RC, Cullins D, Rooney B, Bell T, Lacayo NJ, Heym K, Degar B, Schiff D, Janssen WE, Triplett B, Pui CH, Leung W, Rubnitz JE.
J Immunother Cancer. Mar 20;7(1): 81, 2019. [ Journal Article ]

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