Samuel Ng

Samuel Y. Ng, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Lymphoid Malignancies Branch


Dr. Ng is studying the molecular mechanisms that underlie mature T-cell malignancies in order to improve the treatment of T-cell Non-Hodgkin lymphomas.

Areas of Expertise

Mature T-Cell Malignancies
Lymphoma Pathogenesis

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them.


Selected Key Publications

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

Ng SY, Yoshida N, Christie AL, Ghandi M, Dharia NV, Dempster J, Murakami M, Shigemori K, Morrow SN, Van Scoyk A, Cordero NA, Stevenson KE, Puligandla M, Haas B, Lo C, Meyers R, Gao G, Cherniack A, Louissaint A Jr, Nardi V, Thorner AR, Long H, Qiu X, Morgan EA, Dorfman DM, Fiore D, Jang J, Epstein AL, Dogan A, Zhang Y, Horwitz SM, Jacobsen ED, Santiago S, Ren JG, Guerlavais V, Annis DA, Aivado M, Saleh MN, Mehta A, Tsherniak A, Root D, Vazquez F, Hahn WC, Inghirami G, Aster JC, Weinstock DM, Koch R.
Nat Commun. 9(1): 2024, 2018. [ Journal Article ]

RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice

Ng SY, Brown L, Stevenson K, deSouza T, Aster JC, Louissaint A Jr, Weinstock DM.
Blood. 132(9): 935-947, 2018. [ Journal Article ]

Peripheral T-Cell Lymphoma: Moving Toward Targeted Therapies

Ng SY, Jacobsen ED.
Hematol Oncol Clin North Am. 33(4) : 657-668, 2019. [ Journal Article ]

Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

Yoshida N, Shigemori K, Donaldson N, Trevisani C, Cordero NA, Stevenson KE, Bu X, Arakawa F, Takeuchi M, Ohshima K, Yoda A, Ng SY, Weinstock DM.
Blood. 135(17): 1467-1471, 2020. [ Journal Article ]

Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas

Rolland DCM, Basrur V, Jeon YK, McNeil-Schwalm C, Fermin D, Conlon KP, Zhou Y, Ng SY, Tsou CC, Brown NA, Thomas DG, Bailey NG, Omenn GS, Nesvizhskii AI, Root DE, Weinstock DM, Faryabi RB, Lim MS, Elenitoba-Johnson KSJ.
Proc Natl Acad Sci U S A. 114(25): 6581-6586, 2017. [ Journal Article ]

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