Ross Lake
- Center for Cancer Research
- National Cancer Institute
- Building 37, Room 1066
- Bethesda, MD 20892
- 240-760-6824
- laker@mail.nih.gov
RESEARCH SUMMARY
Ross Lake is the head of the Laboratory of Genitourinary Cancer Pathogenesis (LCGP) Microscopy Core Facility, which provides state-of-the-art equipment, materials, and expertise to researchers in the LGCP. In addition, the Core is open to scientists at the National Cancer Institute. The Core instruments include a Carl Zeiss LSM780 laser scanning confocal microscope, two Carl Zeiss AxioScan Z1 slide scanners, an automated Nikon Ti2 Eclipse widefield microscope, and a Carl Zeiss AxioObserver epifluorescent microscope. The Core provides access to cutting-edge technology and training on the Core's instruments as well as assistance with experimental design.
Areas of Expertise
1) microscopy, 2) immunofluorescence, 3) immunohistochemistry
Ross Lake
Publications
Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration
A novel structure associated with aging is augmented in the DPP6-KO mouse brain
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model
Biography
Ross Lake
Ross Lake joined the LGCP Microscopy Core Facility in the CCR/NCI in 2003. He has extensive experience in cell and molecular biology, immunohistochemistry, immunofluorescence, as well as in microscopy. Ross was appointed as the Head of the LGCP Microscopy Core Facility in 2014.