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Biology & Biophysics of the Nucleus Symposium - October 20-21, 2022

The mission of the Center of Excellence in Chromosome Biology (CECB) is to achieve a comprehensive understanding of the mechanisms involved in chromosome function, how aberrations in chromosomes and chromatin lead to disease and how these defects can be corrected.

Towards achieving the mission, the Biology & Biophysics of the Nucleus Symposium brings together scientists in the fields of chromatin and chromosome biology, with the focus on stem cells, cell development, aging and cancer.

We hope this symposium offers you an opportunity to learn more about the current status of chromosome structure and function in development and disease, to share your research and to discuss the use and implications of these advances for clinical applications.

Organized by: Shalini Oberdoerffer, Ph.D., Gordon Hager, Ph.D., and Dave Levens, M.D., Ph.D.

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Aligned Blog: Celebrating Hispanic Heritage!

Happy Hispanic Heritage Month! For this edition of Aligned, I thought I would celebrate some of my Latino/a/x friends and colleagues here at the Center for Cancer Research. I asked each of them to “Tell me why your Hispanic Heritage is important to you (and something you love about it).” I hope they inspire you to learn more about the many ways in which we have all benefitted from their Hispanic Heritage.

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T-cell imbalance can impact immunotherapy outcomes

The rapid growth of a patient’s cancer following immune checkpoint inhibitor therapy, known as hyperprogressive disease, is an unexpected treatment outcome that is challenging to predict or study. New results show that a T-cell imbalance in the tumor microenvironment can trigger the condition.

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