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Christine Campo Alewine, M.D., Ph.D.

Christine Campo Alewine, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Molecular Biology

RESEARCH SUMMARY

Dr. Alewine is an NIH Lasker Scholar in the Laboratory of Molecular Biology. Her research focuses on identifying new treatments for pancreatic cancer including pancreatic adenocarcinoma, adenosquamous carcinoma, and acinar cell carcinoma. Dr. Alewine is board certified in internal medicine and medical oncology.

Areas of Expertise

1) pancreatic cancer 2) rare exocrine tumors of the pancreas 3) mesothelin 4) immunotoxin

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 

Publications

Selected Recent Publications

Mesothelin-targeted recombinant immunotoxins for solid tumors

Hagerty, B; Pegna, W; Xu, J; Tai, C; Alewine, C.
Biomolecules. 10(7): 973, 2020. [ Journal Article ]

Molecular mediators of peritoneal metastasis in pancreatic cancer

Avula, LR; Hagerty, B; Alewine, C.
Cancer Metastasis Rev.. 2020. [ Journal Article ]

Phase I/II study of mesothelin-targeted immunotoxin LMB-100 with nab-paclitaxel for patients with advanced pancreatic adenocarcinoma

Alewine, C; Ahmad, M; Peer, CJ; Hu, Z; Lee, M-J; Yuno, A; Kindrick, J; Thomas, A; Steinberg, S; Trepel, J; Figg, WD; Hassan, R; Pastan, I.
Clinical Cancer Research. 2019. [ Journal Article ]

Mesothelin enhances tumor vascularity in newly forming pancreatic peritoneal metastases .

Avula, LR; Rudloff, M.; El-Behaedi, S; Arons, D; Albalawy, R; Chen, X; Zhang, X; Alewine, C.
Molecular Cancer Research. 2019. [ Journal Article ]

Protein synthesis inhibition activity of mesothelin targeting immunotoxin LMB-100 decreases concentrations of oncogenic signaling molecules and secreted growth factors

El-Behaedi, S; Landsman, R; Rudloff, M; Kolyvas, E; Albalawy, R; Zhang, X; Bera, T; Collins, K; Kozlov, S; Alewine, C.
Toxins. 10: E447, 2018. [ Journal Article ]

Job Vacancies

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Team

Postbaccalaureate Fellow (CRTA)
Theressa Ewa
Nurse Practitioner (Contr.)
Cristina Mullenix, CRNP
Research Biologist
Xianyu Zhang
Postbaccalaureate Fellow (CRTA)
Samuel Ricci
Postdoctoral fellow (Visiting)
Mayrel Palestino Dominguez, Ph.D.