Christine Campo Alewine, M.D., Ph.D.

Christine Campo Alewine, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Molecular Biology


Dr. Alewine is an NIH Lasker Scholar in the Laboratory of Molecular Biology. Her research focuses on identifying new treatments for pancreatic cancer including pancreatic adenocarcinoma, adenosquamous carcinoma, and acinar cell carcinoma. Dr. Alewine is board certified in internal medicine and medical oncology.

Areas of Expertise

Rare Exocrine Tumors of The Pancreas

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 


Selected Recent Publications

Systemic immune changes accompany combination treatment with immunotoxin LMB-100 and nab-paclitaxel

Pegna GJ, Lee MJ, Peer CJ, Ahmad MI, Venzon DJ, Yu Y, Yuno A, Steinberg SM, Cao L, Figg WD, Donahue RN, Hassan R, Pastan I, Trepel JB, Alewine C
Cancer Medicine. 12: 4236-4249, 2023.
Full-Text Article
[ Journal Article ]

Two rare cancers of the exocrine pancreas: to treat or not to treat like ductal adenocarcinoma?

Skorupan N, Ghabra S, Maldonado JA, Zhang Y, Alewine C
Journal of Cancer Metastasis and Treatment. 9 (5): 2023.
Full-Text Article
[ Journal Article ]

Novel Humanized Mesothelin-Expressing Genetically Engineered Mouse Models Underscore Challenges in Delivery of Complex Therapeutics to Pancreatic Cancers

Hagerty B, O'Sullivan TN, Zhang X, Collins NK, Custer Lawrence W, Bassel LL, Pate N, Xu J, Guerin TM, Kozlov S, Alewine C
Molecular Cancer Therapeutics. 20: 2082-2092, 2021.
Full-Text Article
[ Journal Article ]

Phase I/II study of mesothelin-targeted immunotoxin LMB-100 with nab-paclitaxel for patients with advanced pancreatic adenocarcinoma

Alewine C, Ahmad M, Peer CJ, Hu Z, Lee M-J, Yuno A, Kindrick J, Thomas A, Steinberg S, Trepel J, Figg WD, Hassan R, Pastan I
Clinical Cancer Research. 2019. [ Journal Article ]

Low serum mesothelin in pancreatic cancer patients results from retention of shed mesothelin in the tumor microenvironment

Zhang X, Yu Y, Peer CJ, Landsman R, Skorupan N, Cao L, Alewine C
Translational Oncology. 2022.
Full-Text Article
[ Journal Article ]

Job Vacancies

We have no open positions in our group at this time, please check back later.

To see all available positions at CCR, take a look at our Careers page. You can also subscribe to receive CCR's latest job and training opportunities in your inbox.


Research Biologist
Xianyu Zhang
Postdoctoral fellow (Visiting)
Mayrel Palestino Dominguez, Ph.D.
Postbaccalaureate Fellow (CRTA)
Daniel Ryan, B.S.
Special Volunteer
Neel Panchwagh
OxCam Scholar
Nisita Dutta, M.S.
Clinical Research Nurse
Eve Koehler, R.N.
Staff Clinician
Nebojsa Skorupan, M.D.
Postbaccalaureate Fellow (CRTA)
Krishna Patel, B.S.
Postdoctoral Fellow (Visiting)
Nargis Malik, Ph.D.