Scott M. Norberg, D.O.

Scott M. Norberg, D.O.

  • Center for Cancer Research
  • National Cancer Institute
Center for Immuno-Oncology


Dr. Norberg researches the use of immunotherapy and cellular therapy for a variety of conditions including human papillomavirus-positive (HPV+) cancers and premalignant diseases caused by chronic HPV infection. His research focuses on understanding resistance to immunotherapy and cellular therapies and applying these treatment modalities to other conditions. 

Areas of Expertise

Cell Therapy
Human Papillomavirus
Cervical Cancer
Oropharyngeal Cancer
Anal Cancer

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them.


Selected Recent Publications

TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers

Nagarsheth NB, Norberg SM, Sinkoe AL, Adhikary S, Meyer TJ, Lack JB, Warner AC, Schweitzer C, Doran SL, Korrapati S, Stevanovic S, Trimble CL, Kanakry JA, Bagheri MH, Ferraro E, Astrow SH, Bot A, Faquin WC, Stroncek D, Gkitsas N, Highfill S, Hinrichs CS.
Nat Med. 2021.
Full-Text Article
[ Journal Article ]

Cancer targeting by TCR gene-engineered T cells directed against Kita-Kyushu Lung Cancer Antigen-1

Marcinkowski B, Stevanović S, Helman SR, Norberg SM, Serna C, Jin B, Gkitsas N, Kadakia T, Warner A, Davis JL, Rooper L, Hinrichs CS.
J Immunother Cancer. 7(1): 229, 2019. [ Journal Article ]

Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis

Allen CT, Lee S, Norberg SM, Kovalovsky D, Ye H, Clavijo PE, Hu-Lieskovan S, Schlegel R, Schlom J, Strauss J, Gulley JL, Trepel J, Hinrichs CS.
J Immunother Cancer. 7(1): 119, 2019. [ Journal Article ]

Advances in Adoptive Cell Therapy for Head and Neck Cancer

Scott M Norberg, Christian S Hinrichs
Otolaryngol Clin North Am. Aug;54(4): 761-768, 2021. [ Journal Article ]

Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis

Yvette Robbins, Jay Friedman, Paul E Clavijo, Cem Sievers, Ke Bai, Renee N Donahue, Jeffrey Schlom, Andrew Sinkoe, Christian S Hinrichs, Clint Allen, Houssein Abdul Sater, James L Gulley, Scott Norberg
J Immunother Cancer. Aug;9(8): e003113, 2021. [ Journal Article ]


Nurse Practitioner
Megan Kenyon, CRNP