The CCR Cancer Innovation Laboratory (CIL) is a transdisciplinary hub to explore fundamental biological concepts and mechanisms relevant to cancer. Investigators use molecular, cellular and organismal approaches to probe known cancer mechanisms, pathways and principles and to discover new ones. The CIL also serves as a venue for the development, modification and application of novel technologies in cancer research and closely interacts with technology-centered programs on the Frederick campus including structural biology, chemical biology, bioengineering, small molecule screening and transgenic animals model generation. Research in the CIL is characterized by its highly interdisciplinary nature of bringing together experts from various backgrounds, including immunologists, cell biologists, computational biologists, chemists, geneticists, virologists and cancer biologists and a high degree of innovation, creativity and risk in the questions that are being pursued.