News and Events
Proteins Released from the Nuclei of Dying Cancer Cells Promote Tumor Growth
Material released from dying cancer cells, known as tumor cell nuclear expulsion products (TuNEPs), contains specific proteins that promote the growth of neighboring cancer cells. Targeting these proteins could lead to new treatments that hinder cancer spread and improve patient outcomes.
Read More
Celebrating CCR Careers: Alan Rein, Ph.D.
Alan Rein, Ph.D., is a known expert in the field of viral assembly, particularly in retroviruses like the human immunodeficiency virus (HIV). After an extensive career studying molecular mechanisms of retroviral replication and pathogenesis, he has announced his retirement.
Read More
Clinical trial researching MRI software for mapping prostate cancer
A clinical trial led by Ismail Baris Turkbey, M.D., Senior Clinician in the Molecular Imaging Branch, is researching a software that can analyze radiographic images of the prostate for cancer detection and diagnosis.
Read More
Mutant RAS can shift other proteins’ positions inside cancer cells
Mutant RAS proteins help shuttle other proteins out of the cell nucleus and into the cytoplasm, where some can promote cancerous growth.
Read More
Clinical trial researching combination drug therapy for Ewing sarcoma and rhabdomyosarcoma
A clinical trial led by Christine M. Heske, M.D., Investigator in the Pediatric Oncology Branch, is researching combination drug therapy for adolescents and young adults with Ewing sarcoma and rhabdomyosarcoma.
Read More
Clinical trial researching drug therapy for adults with colorectal or gastroesophageal cancer
A clinical trial led by Nicholas D. Klemen, M.D., Physician-Scientist Early Investigator in the Surgery Branch, is researching drug therapy for adults with colorectal or gastroesophageal cancer.
Read More
Clinical trial researching drug therapy for adults with HIV-related diseases
A clinical trial led by Ramya Ramaswami, M.B.B.S., M.P.H., Lasker Clinical Research Scholar in the HIV and AIDS Malignancy Branch, is researching drug therapy for two HIV-related diseases.
Read More
Clinical trial researching CAR T-cell therapy for leukemia and lymphoma
A clinical trial led by Jennifer N. Brudno, M.D., Associate Research Physician in the Surgery Branch, is researching CAR T-cell therapy for chronic lymphocytic leukemia and small lymphocytic lymphoma.
Read More
Clinical trial researching combination drug therapy for genitourinary tumors
A clinical trial led by Andrea B. Apolo, M.D., Senior Investigator in the Genitourinary Malignancies Branch, is researching combination drug therapy for rare genitourinary tract tumors.
Read More
Chuan Wu appointed to Senior Investigator at CCR
The CCR community congratulates Chuan Wu, M.D., Ph.D., who has been appointed Senior Investigator in the Experimental Immunology Branch. Wu studies the role of intestinal neuroimmune interactions in health and disease. His lab works to understand the cellular and molecular mechanisms of the dynamic interplay between the enteric nervous system and the immune system to build a comprehensive view of intestinal homeostasis and to discover new therapeutics for intestinal inflammatory diseases.
Read More
Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer
Results from a large CCR clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the bladder. Researchers led by Andrea B. Apolo, M.D., Senior Investigator in the Genitourinary Malignancies Branch, found that postsurgical treatment with pembrolizumab (Keytruda), which is approved by the Food and Drug Administration (FDA) for treating at least 18 different cancers, was superior compared with observation.
Read More