Gastrointestinal tumors harbor T cells that recognize patients’ unique tumor antigens

CCR scientists, lead by Steven A. Rosenberg, M.D., Ph.D., have determined that many common gastrointestinal tumors bear mutations capable of eliciting an immune response, suggesting that immunotherapy could be an effective way to treat these common cancers. Read more...

CECB Meeting Info

Registration now open for Chromatin and Cell Fate Decisions in Development, Aging & Cancer

Jan 17, 2019

The Chromatin and Cell Fate Decisions in Development, Aging & Cancer symposium, hosted by the Center of Excellence in Chromosome Biology (CECB), offers an opportunity to learn more about the current status of chromosome structure and function in development and disease, share research and discuss the use and implications of these advances for clinical applications. The mission of CECB is to achieve a comprehensive understanding of the mechanisms involved in chromosome function, how aberrations in chromosomes and chromatin lead to disease and how these defects can be corrected. Towards achieving our mission, this symposium brings together scientists in the fields of chromatin and chromosome biology, with the focus on stem cells, cell development, aging and cancer. Registration deadline is October 31, 2019. Read more...

Registration now open for Chromatin and Cell Fate Decisions in Development, Aging & Cancer
Steve Rosenberg

Steve Rosenberg receives 2019 Nathan Davis Award and Steinman Award

Jan 11, 2019

Steve Rosenberg, M.D., Ph.D., Chief of the Surgery Branch, has received the American Medical Association’s 2019 Dr. Nathan Davis Award for Outstanding Government Service and The American Association of Immunologists’ 2019 Steinman Award for Human Immunology Research. The Nathan Davis Award recognizes individuals who promoted the art and science of medicine via government service and demonstrated outstanding leadership in his/her field. The Steinman Award recognizes an individual who has made significant contributions to the understanding of immune processes underlying human disease pathogenesis, prevention or therapy.  Read more...

Steve Rosenberg receives 2019 Nathan Davis Award and Steinman Award
Neuro-Oncology Branch

Watch new Neuro-Oncology Branch video on NCI YouTube

Jan 10, 2019

The Neuro-Oncology Branch is comprised of an exceptional team of experts across scientific disciplines and medical specialties dedicated to developing new treatments for patients with brain and spine cancers using the latest technologies. Learn more about this department. Read more...

Watch new Neuro-Oncology Branch video on NCI YouTube
Best places to work

Glassdoor recognizes NIH as one of the best places to work

Dec 31, 2018

NIH has been recognized as one of the best places to work by Glassdoor and the Partnership for Public Service. Glassdoor rankings were “determined by the people who know these companies best - their employees.” The Partnership for Public Service rankings were determined by the views of more than 847,000 civil servants from 488 federal organizations on a wide range of workplace topics. Read more...

Glassdoor recognizes NIH as one of the best places to work
NCI connect

View the new NCI-CONNECT video on YouTube

Dec 27, 2018

NCI-CONNECT (Comprehensive Oncology Network Evaluating Rare CNS Tumors) aims to advance the understanding of rare adult central nervous system (CNS) cancers by establishing and fostering patient-advocacy-provider partnerships and networks to improve approaches to care and treatment. Learn more about NCI-CONNECT through this new video. Read more...

View the new NCI-CONNECT video on YouTube
Stephen Katz

In Memoriam: Stephen Katz, M.D., Ph.D.

Dec 21, 2018

Stephen Katz, M.D., Ph.D., Director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases and former Senior Investigator in the Dermatology Branch at the Center for Cancer Research, died suddenly on December 20, 2018, at the age of 77. Dr. Katz served as a senior investigator in the Dermatology Branch from 1974-2014 and became acting chief in 1977. In 1980, he became chief of the branch, a position he held until 2002. “Steve had extraordinary abilities in research, administration and training,” said NCI Deputy Director Doug Lowy, M.D. “For example, he made the Dermatology Branch the place to come for training in dermatology research and was responsible for training many American and foreign leaders in the field.” Read more...

In Memoriam: Stephen Katz, M.D., Ph.D.
Steve Rosenberg

Steve Rosenberg featured in National Geographic article on personalized medicine

Dec 20, 2018

Steve Rosenberg, M.D., Ph.D., Chief of the Surgery Branch, was recently featured in a National Geographic article on how personalized medicine is transforming health care. The article highlights Judy Perkins, a metastatic breast cancer patient who was successfully treated with an experimental immunotherapy by Dr. Rosenberg.   Read more...

Steve Rosenberg featured in National Geographic article on personalized medicine
Ken Kraemer

Ken Kraemer discusses xeroderman pigmentosum with various media outlets

Dec 19, 2018

Kenneth Kraemer, M.D., Senior Investigator in the Laboratory of Cancer Biology and Genetics, has been featured by several media outlets discussing xeroderma pigmentosum (XP), a very rare skin disorder that makes a person highly sensitive to sunlight and prone to developing skin cancers. Dr. Kraemer provided some background on the dangers of living with XP for a Russia Today documentary and discussed the use of three large databases to estimate the prevalence of defective DNA repair variants in the United States with MedicalResearch.com. Read more...

Ken Kraemer discusses xeroderman pigmentosum with various media outlets
Horizons cover

New CCR publication, Horizons, is now available

Dec 18, 2018

As Nobel-Prize-winning physicist Niels Bohr once said, “Prediction is very difficult, especially about the future.” Yet, several areas of research that promise new understanding and treatments of cancer are coming into view. In this magazine, we highlight several areas of investigation likely to shape future research conducted in CCR. The collection in Horizons is by no means complete but seeks to capture some of the major areas that will influence our future work. Read more...

New CCR publication, Horizons, is now available
KRAS structure

Clinical trials evaluate T-cell transfer therapy for cancers with a mutated KRAS gene

Dec 17, 2018

KRAS mutations are present in up to a quarter of all human cancers, and eligible patients in a new clinical trial will undergo gene transfer therapy that uses their own blood cells. Investigators want to see if anti-KRAS T cells can make tumors shrink and whether this therapy has tolerable side effects.  Read more...

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