2024 - 2025 Annual Highlights

This issue of Milestones highlights some of our scientific advances in FY 2024-2025.

Researchers pinpoint a critical protein in the liver that controls gut health and repair. 

Having more diverse HLA genes is better for immune control of HIV. 

A novel drug combination likely cured more than a third of study participants of their lymphoma. 

Researchers identify a gene critical for embryonic development.

A personalized approach to cellular immunotherapy helps shrink solid tumors.  

Images of a bacterial motor show how it can reverse direction with the flip of a biological switch. 

New insights reveal how bone marrow cells impact the survival of plasma cells and their antibodies. 

A novel gene therapy helps eliminate recurring respiratory growths in patients — and the frequent surgeries they required. 

A genome-wide screen drills down to gene segments to find out which ones matter for cell fitness. 

Liver cells divvy up metabolic tasks to take advantage of available nutrients.   

An AI tool predicts tumor response to targeted therapy using single-cell datasets. 

A novel gene therapy approach proves safe and effective for children with Wiskott-Aldrich syndrome. 

A new method makes therapeutic cancer vaccines more reliably effective in mice. 

New faculty contribute to our work of making breakthrough scientific discoveries to find cures and treatments for cancer. We also recognize current faculty who have started new roles within CCR.

We are proud of our CCR awardees who represent a spectacular array of accomplishments.

Take a look at our year as told by the numbers to see a snapshot of the breakthrough scientific discoveries and important work happening at CCR.