News and Events

In Memoriam: S. Perwez Hussain, Ph.D. (1960 - 2023)

The CCR community is profoundly saddened by the passing of S. Perwez Hussain, Ph.D., Senior Investigator in the Laboratory of Human Carcinogenesis. He died on November 24, 2023, after living with stage 4 colon cancer for many years.

FDA grants orphan drug designation to indotecan for the treatment of glioma

The U.S. Food and Drug Administration (FDA) granted orphan drug status to LMP400 (indotecan) for use in patients with malignant glioma, a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).

Clinical trial researches combination drug therapy for myelodysplastic syndromes

A clinical trial led by Steven Z. Pavletic, M.D., Ph.D., Senior Clinician in the Immune Deficiency Cellular Therapy Program, is researching a combination drug therapy for myelodysplastic syndromes.

Six years after preventive surgery: a patient’s future without stomach cancer

Faced with a high risk of developing stomach cancer, David Fogel chose to undergo preventive surgery as part of an NIH research study. Six years later, David is thriving, and so is the research that was made possible by his participation.

Population-specific tumor mutation patterns may reflect breast cancer health disparities

African American, European American and Kenyan patients with breast cancer have different patterns of tumor mutations.

Aligned Blog: Celebrating Native American Heritage Month: in conversation with Karina Walters, Ph.D., M.S.W.

To celebrate Native American Heritage Month, we spoke with Karina Walters, Ph.D., M.S.W., Director of the NIH Tribal Research Health Office (THRO). Dr. Walters, an enrolled member of the Choctaw Nation of Oklahoma, shares what motivates her in working to improve the lives of Indigenous People, her vision for THRO and her own experience as a researcher.

Clinical trial researches combination drug and vaccine for mouth cancer

A clinical trial led by Charalampos S. Floudas, M.D., D.M.Sc., M.S., Assistant Research Physician in the Center for Immuno-Oncology, is researching a combination therapy for cancers of the mouth.

New insights show faulty immune cells are trained to become healthy

Researchers traditionally believed faulty T cells that have the potential to attack someone’s own tissues were eliminated before the cells leave the thymus. Now, research in mice shows that these autoreactive cells are evicted from the thymus and can mature into healthy cancer-fighting cells in the body’s peripheral tissues. This basic science discovery holds important implications for our understanding of autoimmune diseases and cancer.

New technology assists T-cell therapy in eradicating solid tumors in mice

A new technology targeted at T-cell therapy may help immunotherapy overcome the treatment-hindering environment inside solid tumors.

Clinical trial researches immunotherapy for cancers of the reproductive system

A trial led by Andrew Blakely, M.D., Assistant Research Physician in the Surgical Oncology Program, is researching immunotherapy for adults with cancers of the reproductive system.

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