CCR Cancer Moonshot Projects

CCR is proud to participate in the Cancer Moonshot, one of NCI’s key initiatives. The Cancer Moonshot seeks to accelerate cancer research to make more therapies available to more patients, while also improving our ability to prevent cancer and detect it at an early stage. Moonshot projects are based on a 2016 Blue Ribbon Panel Report, which describes 10 transformative research recommendations for achieving the Cancer Moonshot's ambitious goal of making a decade's worth of progress in cancer prevention, diagnosis, and treatment in just 5 years. Below are CCR’s funded projects:

CCR Moonshot Project	Blue Ribbon Panel Recommendation	CCR Project Leaders
Image Rare Tumor Patient Engagement Network Goal: Build a national network to study selected rare pediatric and adult tumors and develop a network of clinical trials. NCI-CONNECT: Comprehensive Oncology Network Evaluating Rare CNS Tumors. NCI-CONNECT aims to advance the understanding of rare adult central nervous system (CNS) cancers by establishing and fostering patient-advocacy-provider partnerships and networks to improve approaches to care and treatment. MyPART: Moonshot Pediatric, Adolescent, and Adult Rare Tumors Network. MyPART focuses on research across a range of pediatric, adolescent, and young adult rare solid tumors.	Establish a network for direct patient involvement	Terri Armstrong Mark Gilbert Karlyne Reilly Brigitte Widemann
Image Cell-based Therapy Center Goal: Build a trans-NIH cell-based therapy center for development and dissemination of cutting-edge immunotherapy approaches.	Create a translational science network devoted exclusively to immunotherapy.	Tim Greten
Image NCI Program for Natural Products Discovery Goal: Develop a library of 1 million pre-fractionated natural product pools to be made available for screening to the extramural community and to provide natural products screening expertise and infrastructure.	Develop new cancer technologies	Barry O’Keefe Joel Schneider
Image High-Throughput Discovery and Widespread Dissemination of T Cell Receptor Gene Therapy for Human Cancers Goal: Catalyze intramural and extramural T Cell Receptor (TCR) gene therapy research.	Create a translational science network devoted exclusively to immunotherapy	Kazusa Ishii
CCR Moonshot Clinical Trials	Blue Ribbon Panel Recommendation	CCR Project Leaders
Image Graft-Versus-Host Disease (GVHD) Symptom Management Goal: Development and psychometric testing of a pediatric chronic symptom scale (PCSS).	Minimize cancer treatment’s debilitating side effects	Sandra Mitchell, DCCPS Lori Wiener
Image Prostate Imaging Clinical Trial Goal: To determine the clinical impact of PET imaging of prostate-specific membrane antigen (PSMA) on patients with high-risk prostate cancer who have negative conventional imaging (CT and bone scan).	Develop new cancer technologies	Pete Choyke Doug Figg James Gulley Fatima Karzai Ravi Madan

Breadcrumb

Rare Tumor Patient Engagement Network

Cell-based Therapy Center

NCI Program for Natural Products Discovery

High-Throughput Discovery and Widespread Dissemination of T Cell Receptor Gene Therapy for Human Cancers

Graft-Versus-Host Disease (GVHD) Symptom Management

Prostate Imaging Clinical Trial