Kazusa Ishii, M.D., M.P.H.

Kazusa Ishii, M.D., M.P.H.

  • Center for Cancer Research
  • National Cancer Institute
Center for Immuno-Oncology


Dr. Kazusa Ishii researches cell therapy for various hematologic malignancies and non-malignant diseases. Her research focuses on 1) identification of therapeutically targetable antigens, 2) discovery, pre-clinical development and clinical translation of novel cell therapies, and 3) improving our mechanistic understanding of how T-cell-mediated therapies and the host’s immune environment affect clinical responses and disease phenotypes.

Areas of Expertise

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 


Selected Recent Publications

Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients

Ishii K, Pouzolles M, Chien CD, Erwin-Cohen RA, Kohler ME, Qin H, Lei H, Kuhn S, Ombrello AK, Dulau-Florea A, Eckhaus MA, Shalabi H, Yates B, Lichtenstein DA, Zimmermann VS, Kondo T, Shern JF, Young HA, Taylor N, Shah NN, Fry TJ.
J Clin Invest. 130(10): 5425-5443, 2020. [ Journal Article ]

Murine pre-B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor

Qin H, Ishii K, Nguyen S, Su PP, Burk CR, Kim BH, Duncan BB, Tarun S, Shah NN, Kohler ME, Fry TJ.
Blood. 132(18): 1899-1910, 2018. [ Journal Article ]

Novel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic)

Ishii K, Barrett AJ.
Ther Adv Hematol. 7(1): 17-39, 2016. [ Journal Article ]

Impact of HLA-Mismatch in Unrelated Donor Hematopoietic Stem Cell Transplantation: A Meta-Analysis

Kekre N, Mak KS, Stopsack KH, Binder M, Ishii K, Brånvall E, Cutler CS.
Am J Hematol. 91(6): 551-5, 2016. [ Journal Article ]

A prospective analysis of blood donation history and risk of non-Hodgkin lymphoma

Ishii K, Birmann BM, Zhang X, Giovannucci E, Bertrand KA.
Leuk Lymphoma. 57(6): 1423-8, 2016. [ Journal Article ]

Job Vacancies

Position Degree Required Contact Name Contact Email
Post-doctoral Fellow - immunotherapy, immunology, T cell receptor Ph.D. or equivalent Kazusa Ishii


Postbaccalaureate Fellow
Kilyna Nguyen


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