Our Discoveries

Papillary Renal Cell

Understanding Papillary Renal Cell Carcinoma

Renal cell carcinoma (RCC), the most common form of kidney cancer in adults, is not a single disease but rather a collection of different tumor types driven by distinct genetic changes that arise within the same tissue. Learn more about the importance of understanding papillary renal cell carcinoma…

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Insight into Prostate Cancer Stem Cells

The majority of prostate cancers display a luminal phenotype, but little is known about the stem/progenitor properties of transformed prostate cells. Learn more about the insight into prostate cancer stem cells…

News Inquiries

If you are interested in interviewing a CCR scientist, OR you are a scientist who has been contacted by a member of the media, please contact the NCI Media Relations Branch at ncipressofficers@mail.nih.gov or by phone at 301-496-6641.

Scientists at Work


A Brake for Cancer

A common molecular driver of lung cancer. somatic mutations in the epidermal growth factor receptor (EGFR) can be differentially targeted with tyrosine kinase inhibitors (TKIs) such as gefitinib (Iressa) or erlotinib (Tarceva).  Patients with such mutations in EGFR respond dramatically to these inhibitors, but all develop acquired drug resistance and eventually progress.  Read more...

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The Power of Families

Many diseases that are seemingly sporadic in the population at large cluster in certain families. Where genetic lineage can be established, researchers have an opportunity to discover specific DNA mutations that might give insight into not only the familial forms of the disease, but also the more widespread pathological mechanisms. Read more...