Natalie Porat-Shliom, Ph.D.

Natalie Porat-Shliom, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Thoracic and GI Malignancies Branch


Dr. Porat-Shliom is a cell biologist with expertise in light microscopy techniques, particularly, intravital microscopy. Her lab uses a combination of molecular, biochemical and imaging approaches to investigate the principles underlying mitochondrial structure and function and the changes under pathological conditions such as Non-Alcoholic Fatty Liver Disease.

Areas of Expertise

Mitochondria Biology
Intravital Microscopy
Liver Physiology

CCR Liver Cancer Program

A multidisciplinary research network dedicated to improving early detection, diagnosis, prognosis and treatment of liver cancer.


LKB1 acts as a critical brake for the glucagon-mediated fasting response

Suehelay Acevedo-Acevedo,Megan L. Stefkovich,Sun Woo Sophie Kang,Rory P. Cunningham,Constance M. Cultraro,Natalie Porat-Shliom
Hepatology Communications. 2022.
Full-Text Article
[ Journal Article ]

Liver Zonation - Revisiting Old Questions With New Technologies

Rory P Cunningham and Natalie Porat-Shliom
Front Physiol.. 2021.
Full-Text Article
[ Journal Article ]

Intravital Microscopy for the Study of Hepatic Glucose Uptake

Megan L Stefkovich, Sun Woo Sophie Kang, Natalie Porat-Shliom
Curr Protoc. 1(5): e139, 2020.
Full-Text Article
[ Journal Article ]

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression.

Danfeng Cai, Daniel Feliciano, Peng Dong, Eduardo Flores, Martin Gruebele, Natalie Porat-Shliom, Shahar Sukenik, Zhe Liu, and Jennifer Lippincott-Schwartz
Nat Cell Biol. 21(12): 1578-1589, 2019.
Full-Text Article
[ Journal Article ]

Mitochondrial populations exhibit differential dynamic responses to increased energy demand during exocytosis in vivo

Porat-Shliom N, Harding O, Malec L, Narayan K, Weigert R
iScience. 11: 440–449, 2019. [ Journal Article ]

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Post Baccalaureate Fellow (IRTA/CRTA)
Lauryn Brown, B.S.
Mercedes Cornelius
Pre-doctoral IRTA (Graduate student)
Mercedes Cornelius, B.S.
Senior Research Assistant
Constance M Cultraro, Ph.D.
Colin Miller
Post Baccalaureate Fellow (IRTA/CRTA)
Colin Miller, B.S.


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