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Jack Shern, M.D.

Jack F. Shern, M.D.

  • Center for Cancer Research
  • National Cancer Institute
Lasker Clinical Research Scholar
Pediatric Oncology Branch
Head, Tumor Evolution and Genomics Section

RESEARCH SUMMARY

Dr. Jack Shern is a physician scientist within the Pediatric Oncology Branch. His research is focused on defining and developing precision therapies targeting the genetic mutations that drive tumorigenesis. Most recently, his efforts have turned towards using single cell sequencing to discover tumor subclonal populations that are responsible for relapse and refractory disease. He is actively engaged in the Children's Oncology Group, working on pediatric soft tissue sarcomas to investigate the utility of using mutational information as biomarkers for the diagnosis and management of pediatric rhabdomyosarcoma.

Areas of Expertise

Rhabdomyosarcoma
Fusion Oncogenes

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Publications

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Team

Haiyan Lei, PhD
Bioinformatics Specialist (Contr.)
Haiyan Lei, Ph.D.
Bega Murray, PhD
Postdoctoral Fellow
Bega Murray, PhD
George Annor, PhD
Postdoctoral Fellow
George Annor, PhD
Ukhyun Jo, PhD
Research Fellow
Ukhyun Jo, PhD
Post baccalaureate fellow
Shafaq Ahmed
Rhea Pandit
Post baccalaureate fellow
Rhea Pandit
Post Baccalaureate Fellow
Chloe Sachs
Bioinformatic Analyst
Ying Wu

Alumni

Xiyuan Zhang, PhD
Xiyuan Zhang, PhD