Breadcrumb

Naomi Taylor, M.D., Ph.D.

Naomi Taylor, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Pediatric Oncology Branch

RESEARCH SUMMARY

The interest of our laboratory is to combine fundamental and translational approaches in order to (1) Elucidate the metabolic mechanisms regulating T cell differentiation and anti-tumor effector responses, (2) Define the elements in the thymus microenvironment that enhance thymocyte differentiation from hematopoietic stem cells (HSCs), (3) Understand the metabolic regulation of tumor growth and its impact on HSC differentiation, and (4) Develop novel immunotherapy strategies for the treatment of pediatric cancer and  immunodeficiency patients.

Areas of Expertise

1) cancer immunology, 2) hemato-metabolism, 3) hematopoietic stem cell transplantation, 4) immunotherapy, 5) thymocyte differentiation, 6) gene therapy

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 

Publications

Selected Key Publications

Women in immunology: 2020 and beyond

Pierce SK, Schwartzberg PL, Shah NN, Taylor N.
Nat Immunol. 21(3): 254-8, 2020. [ Journal Article ]

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification

Oburoglu L, Tardito S, Fritz V, De Barros SC, Merida P, Craveiro M, Mamede J, Cretenet G, Mongellaz C, An X, Klysz D, Touhami J, Battini J-L, Dardalhon V, Zimmermann VS, Mohandas N, Gottlieb E, Sitbon M, Kinet S, and Taylor N.
Cell Stem Cell. 15(2): 169-184, 2014. [ Journal Article ]

Glut1-mediated glucose transport regulates HIV infection

Loisel-Meyer S, Swainson L, Craveiro M, Oburoglu L, Mongellaz C, Costa C, Martinez M, Cosset FL, Battini JL, Herzenberg LA, Herzenberg LA, Atkuri KR, Sitbon M, Kinet S, Verhoeyen E, and Taylor N.
Proc Natl Acad Sci U S A. 109(7): 2549-2554, 2012. [ Journal Article ]

Intrathymic transplantation of bone marrow derived progenitors provides long-term thymopoiesis

Vicente, R, Adjali O, Jacquet C, Zimmermann VS,* and Taylor N.*
Blood. 115(10): 1913-1920, 2010. [ Journal Article ]

Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C

Montel-Hagen A, Kinet S, Manel N, Mongellaz C, Prohaska R, Battini JL, Delaunay J, Sitbon M, and Taylor N.
Cell. 132(6): 1039-1048, 2008. [ Journal Article ]

Job Vacancies

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Team

Biologist
Christopher D. Chien, Ph.D.
Postdoctoral Fellow (Visiting)
Taisuke Kondo, Ph.D.
Postdoctoral Fellow (Visiting)
Marie C. Pouzolles, Ph.D.
Senior Research Assistant
Haiying Qin
Scientist (Contr.)
Angela Hui Su