Deborah E. Citrin, M.D.
- Center for Cancer Research
- National Cancer Institute
- Building 10 - Hatfield CRC, Room B2-3500
- Bethesda, MD 20892
Dr. Citrin is a clinician and translational researcher in the Radiation Oncology Branch at the National Cancer Institute. Dr. Citrin’s clinical and laboratory research focus on two main themes: 1) predicting which tumors are resistant to killing by radiation, and in turn, targeting these tumors more effectively with novel drug radiation combinations, and 2) understanding the mechanisms of normal tissue injury from radiation. Dr. Citrin is particularly interested in developing strategies to enhance the capacity of radiation to kill tumor cells while protecting normal tissue from the side effects of radiation treatment. Much of her laboratory work has focused on aging in tissue exposed to radiation through stem cell senescence.
Dr. Citrin leads the Prostate Radiotherapy program at the National Cancer Institute. She is involved in the clinical care of patients with genitourinary cancers (prostate and bladder), gastrointestinal cancers, and thoracic malignancies. Dr. Citrin is board certified by the American Board of Radiology.
Areas of Expertise
Information for Patients
Learn more about the Radiation Oncology Prostate Cancer Clinical Research Team and clinical trials.
Senescence-associated tumor growth is promoted by 12-Lipoxygenase.
Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect
IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis.
12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation
Deborah E. Citrin, M.D.
Dr. Citrin is a graduate of the Duke University School of Medicine, where she also participated in the Howard Hughes Medical Student Research Fellow Program. She completed an Internship in Internal Medicine at Washington Hospital Center and completed her residency training at the National Cancer Institute. She joined the Radiation Oncology Branch in 2005 and is currently a Senior Investigator in the Radiation Oncology Branch. Dr. Citrin also serves as a CCR Deputy Director.
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