Peritoneal carcinomatosis occurs when tumors have spread to the lining of the abdomen from other cancers. This can occur with cancers of the appendix, colon or ovary, as well as mesothelioma, a cancer caused by asbestos. A clinical trial led by Andrew M. Blakely, M.D., Assistant Research Physician in the Surgical Oncology Program, is researching a combination drug therapy for the disease. The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.
Clinicaltrials.gov identifier: NCT05185947
NCI Protocol ID: NCI000237
Official Title: Phase II Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Ovarian, Colorectal, or Appendiceal Cancer
The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.