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Romina Goldszmid, Ph.D.

Romina Goldszmid, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

Dr. Goldszmid has a long standing interest in understanding the mechanisms governing the development, functional maturation and dynamics of the mononuclear phagocyte cellular network [e.g. dendritic cells, monocytes and macrophages] that plays an instrumental role in host defense. In particular, her research focuses on linking the microbiome, mononuclear phagocyte development, and cancer and infectious diseases with the ultimate goal of identifying new potential therapeutic interventions to improve cancer treatment.

Areas of Expertise

Mononuclear Phagocytes (dendritic cells, macrophages and monocytes)
Inflammation
Toxoplasma Gondii
Innate Immunity

Publications

Selected Recent Publications

Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy

Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G
Nat Med. [Epub ahead of print], 2020. [ Journal Article ]

IFNAR1 Degradation: A New Mechanism for Tumor Immune Evasion?

Araya RE, Goldszmid RS
Cancer Cell. 31(2): 161-3, 2017. [ Journal Article ]

Two Bugs a NOD Away from Improving Cancer Therapy Efficacy

Araya RE, Goldszmid RS
Immunity. 45(4): 714-16, 2016. [ Journal Article ]

Microbiota modulation of myeloid cells in cancer therapy

Goldszmid RS, Dzutsev A, Viaud S, Zitvogel L, Restifo NP, Trinchieri G.
Cancer Immunol Res. 3(2): 103-9, 2015. [ Journal Article ]

Host immune response to infection and cancer: unexpected commonalities

Goldszmid RS, Dzutsev A, and Trinchieri G.
Cell Host Microbe. 15(3): 295-305, 2014. [ Journal Article ]

Job Vacancies

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Team

Postdoctoral Fellow (Visiting)
Romina Araya, Ph.D.
Biologist (Contr.)
Quanyi Chen
Predoctoral Fellow (Graduate Student)
Khiem Lam, B.S.
Postdoctoral Fellow (Visiting)
Amelie Lopes, Ph.D.