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Vijaya Kumar Pidugu, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Cancer Biology and Genetics

RESEARCH SUMMARY

Dr. Vijaya Kumar Pidugu has expertise in dissecting molecular signaling mechanisms of cancer response, acquired resistance to biological therapeutics, characterizing preclinical candidates, and molecular target discovery using a variety of cell-based and animal models.  

For his Ph.D., Dr. Pidugu studied the oncogenic role of IFIT1 and IFIT3 in oral squamous cell carcinoma metastasis and drug resistance.

As a postdoctoral fellow in Dr. Ji Luo’s lab, he is investigating Kras-driven lung adenocarcinoma progression and drug resistance mechanisms in 3D-lung organoid models by targeting mutant Kras in mouse alveolar epithelial type 2 cells (AEC-2)-derived lung organoids by combinatorial drug screening.

Areas of Expertise

1. Cancer biology, 2. Molecular toxicology, 3. 3D-organoid models