Photo of Victor Zhurkin taken in 2022

Victor B. Zhurkin, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Laboratory of Cell Biology


Dr. Zhurkin obtained his Ph.D. in molecular biophysics from the Moscow Physico-Technical Institute, and D.Sc. degree from the Lomonosov Moscow State University (Russia), and continued his research on DNA conformational mechanics in the Engelhardt Institute of Molecular Biology (Moscow, Russia). Since 1989, he has been at the National Cancer Institute, where he has studied structural aspects of the protein-DNA interactions in large nucleoprotein assemblages such as nucleosomes, the Gal-repressosome, recombination filaments, transcription elongation complexes, and a tetrameric p53-DNA complex.

Areas of Expertise

Sequence-Dependent DNA Deformability
Protein-DNA Interactions
Nucleosome Positioning
DNA Topology in Chromatin and Gene Regulation


Selected Recent Publications

Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy

Norouzi D, Zhurkin VB.
Biophys J. 2018 Nov 6;115(9):1644-1655. doi: 10.1016/j.bpj.2018.06.032.. [ Journal Article ]

DNA topology in chromatin is defined by nucleosome spacing

Nikitina T, Norouzi D, Grigoryev SA, Zhurkin VB.
Sci Adv. 2017 Oct 27;3(10):e1700957. doi: 10.1126/sciadv.1700957. eCollection 2017 Oct.. [ Journal Article ]

DNA-RNA interactions are critical for chromosome condensation in Escherichia coli

Qian Z, Zhurkin VB, Adhya S.
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12225-12230. doi: 10.1073/pnas.1711285114. [ Journal Article ]

Topological polymorphism of the two-start chromatin fiber

Norouzi D, Zhurkin VB.
Biophys J. 2015 May 19;108(10):2591-2600. doi: 10.1016/j.bpj.2015.04.015.. [ Journal Article ]

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Research Assistant (Contr)
Tatiana Nikitina
Postdoctoral Fellow (CRTA)
Wilfried Guiblet


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