Steven Pavletic, M.D., Ph.D.

Steven Z. Pavletic, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Pavletic is a an expert in chronic graft-versus-host disease (cGVHD); his clinical studies focus on improving treatment for patients with cGVHD. Dr. Pavletic has led national and international efforts to develop consensus guidelines for cGVHD clinical trials. Currently, he directs the NIH cGVHD Study Group and the NIH Myeloid Malignancies Clinical Program, which is investigating myelodysplastic syndromes (MDS) and secondary or therapy-related acute myelogenous leukemia (AML).

Areas of Expertise

Chronic Graft Versus Host Disease (cGVHD)
Myelodysplastic Syndromes (MDS)

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 

Clinical Trials


Selected Publications

Quality of Life in Patients With Skin of Color and Chronic Graft-vs-Host Disease

Smith ZI, Rosenstein RK, Banerjee S, Pichard DC, Pavletic SZ, Cowen EW.
JAMA Dermatol. 156(5): 589-90, 2020. [ Journal Article ]

T Cells Genetically Modified to Express an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma

Brudno JN, Maric I, Hartman SD, Rose JJ, Wang M, Lam N, Stetler-Stevenson M, Salem D, Yuan C, Pavletic S, Kanakry JA, Ali SA, Mikkilineni L, Feldman SA, Stroncek DF, Hansen BG, Lawrence J, Patel R, Hakim F, Gress RE, Kochenderfer JN.
J Clin Oncol. 36(22): 2267-80, 2018. [ Journal Article ]

An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD

Poe JC, Jia W, Su H, Anand S, Rose JJ, Tata PV, Suthers AN, Jones CD, Kuan PF, Vincent BG, Serody JS, Horwitz ME, Ho VT, Pavletic SZ, Hakim FT, Owzar K, Zhang D, Blazar BR, Siebel CW, Chao NJ, Maillard I, Sarantopoulos S.
Blood. 130(19): 2131-45, 2017. [ Journal Article ]

Characterization and Risk Factor Analysis of Osteoporosis in a Large Cohort of Patients with Chronic Graft-versus-Host Disease

Pirsl F, Curtis LM, Steinberg SM, Tella SH, Katić M, Dobbin M, Hsu J, Hakim FT, Mays JW, Im AP, Pulanić D, Mitchell SA, Baruffaldi J, Masuch L, Halverson DC, Gress RE, Barsony J, Pavletic SZ.
Biol Blood Marrow Transplant. 22(8): 1517-24, 2016. [ Journal Article ]

Prevalence and determinants of fatigue in patients with moderate to severe chronic GvHD

Im A, Mitchell SA, Steinberg SM, Curtis L, Berger A, Baird K, Kuzmina Z, Joe G, Comis LE, Juckett M, Avila D, Baruffaldi J, Masuch L, Pirsl F, Pavletic SZ
Bone Marrow Transplant. 51(5): 705-12, 2015. [ Journal Article ]

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Noa Holtzman
Clinical Collaborator
Noa G. Holtzman, M.D.
Laboratory Technician (Contr.)
Filip Pirsl, B.S.
Postbaccalaureate (CRTA2) Fellow
Aaron Zhao, B.S.
Special Volunteer
Annie Im, M.D.
Nurse Practitioner (Contr.)
Grace Li