Markku Martti Miettinen, M.D., Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 10, Room 2S235C
- Bethesda, MD 20892
- 301-480-8947
- miettinenmm@mail.nih.gov
RESEARCH SUMMARY
The mission of Division of the Surgical Pathology is to provide the most accurate and timely pathology consultations serving the clinical trials of the NCI/NIH using the latest technology integrated in morphologic evaluation. Dr. Miettinen's research interests include pathology of soft tissue tumors and gastrointestinal stromal tumor (GIST). His group has delineated the prognostication system for GIST and clinicopathologic profile or GISTs of different sites. Current work includes prognostic, molecular, and biomarker analysis of sporadic and syndromic GISTs and evaluation of new diagnostic markers for soft tissue sarcomas and related tumors.
Areas of Expertise
Markku Martti Miettinen, M.D., Ph.D.
Research
The mission of Division of the Surgical Pathology is to provide the most accurate and timely pathology consultations serving the clinical trials of the NCI/NIH using the latest technology integrated in morphologic evaluation. Dr. Miettinen's research interests include pathology of soft tissue tumors and gastrointestinal stromal tumor. His group has delineated the prognostication system for GIST and clinicopathologic profile or GISTs of different sites. Current work includes prognostic, molecular, and biomarker analysis of sporadic and syndromic GISTs and evaluation of new diagnostic markers for soft tissue sarcomas and related tumors.
Publications
- Bibliography Link
- View Dr. Miettinen's PubMed Summary.
Anaplastic Lymphoma Kinase Gene Rearrangement in Children and Young Adults With Mesothelioma
A Phase II Trial of Vandetanib in Children and Adults with Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor
Primary malignant melanoma of esophagus: clinicopathologic characterization of 20 cases including molecular genetic profiling of 15 tumors
ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Myxoinflammatory fibroblastic sarcoma: a clinicopathologic analysis of 104 cases, with emphasis on predictors of outcome
Biography
Markku Martti Miettinen, M.D., Ph.D.
Dr. Miettinen earned the degrees of M.D. in 1977 and Ph.D. in 1983 from the University of Helsinki Medical School, where he also completed his residency in anatomic pathology in 1982. Previously, he served as a Chairman and Registrar and Distinguished Scientist of the Department of Soft Tissue and Orthopedic Pathology in the Armed Forces Institute of Pathology for 15 years and Professor of Pathology and attending pathologist at the Jefferson Medical College and Thomas Jefferson University Hospital. He was also an attending pathologist and assistant professor of pathology at the University of Helsinki and its affiliated hospitals. He serves on the editorial boards of American Journal of Surgical Pathology, Human Pathology, The Journal of Pathology, and Applied Immunohistochemistry and Molecular Morphology.
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Covers
Modern Soft Tissue Pathology
This book comprehensively covers modern soft tissue pathology and includes both tumors and non-neoplastic entities. Soft tissues make up a large bulk of the human body, and they are susceptible to a wide range of diseases. Many soft-tissue tumors are biologically very aggressive, and the chance of them metastasizing to vital organs is quite high. In recent years, the outlook for soft-tissue cancers has brightened dramatically due to the increased accuracy of the pathologist's tools. All methods of diagnosis are covered here, with an emphasis on the newest immunoassays and other genetic, molecular, and immunologic diagnostic modalities. This book's systematic description of benign and malignant primary soft tissue tumors with didactic, comprehensive panels of illustrations allows the reader to formulate a complete understanding of the morphology of tumor entities at one glance. The book covers both the most common tumor entities and more unusual diseases using more than 1,500 color images, making it a resource for beginning and senior pathologists.
M. Miettenen, ed. (2010). Modern Soft Tissue Pathology Tumors and Non-Neoplastic Conditions. New York, NY: Cambridge University Press.