picture of Mahesh Agarwal

Mahesh Agarwal, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
HIV Dynamics and Replication Program


Mahesh earned his Ph.D. at the Indian Institute of Technology in Guwahati in 2018. His doctoral work focused on developing a therapeutic protein based on Diphtheria toxin for the treatment of cancer. During his time as a postdoctoral fellow at the National Cancer Institute, Mahesh has worked on developing DNA-based vaccines for COVID-19 and exploring the durability of antibody responses to SARS-CoV-2 following infection or vaccination. He is now investigating mechanisms by which retroviruses, including HIV-1, antagonize the antiviral protein IFITM3. In addition to his research, Mahesh is passionate about teaching, mentoring, and communicating science.

Areas of Expertise

1) IFITM 2) immune evasion 3) viral accessory proteins 4) host-virus coevolution 5) HIV-1