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Jairaj K. Acharya, MBBS, Ph.D.

Jairaj K. Acharya, MBBS, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

We are interested in understanding the complex interrelationship between phospholipid (PL) and sphingolipid (SL) metabolism and metabolic signaling in vivo. Our studies are investigating several aspects of lipid signaling in Drosophila.

Areas of Expertise

Phospholipid Metabolism
Sphingolipid Metabolism
Metabolic Signaling

Publications

Selected Recent Publications

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila.

Alka Singh, Kandahalli Venkataranganayaka Abhilasha, Kathya R Acharya, Haibo Liu, Niraj K Nirala, Velayoudame Parthibane, Govind Kunduri, Thiruvaimozhi Abimannan, Jacob Tantalla, Lihua Julie Zhu , Jairaj K Acharya, Usha R Acharya
Nat Commun. . 15(1):4410.: 2024.
Full-Text Article
[ Journal Article ]

Sphingolipid biosynthesis is essential for metabolic rewiring during TH17 cell differentiation.

Thiruvaimozhi Abimannan, Velayoudame Parthibane, Si-Hung Le, Nagampalli Vijaykrishna, Stephen D Fox, Baktiar Karim, Govind Kunduri, Daniel Blankenberg, Thorkell Andresson, Takeshi Bamba, Usha Acharya, Jairaj K Acharya
Science Advances. Vol 10, Issue 17: 2024.
Full-Text Article
[ Journal Article ]

Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis

Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K. Acharya
PLOS Biology. 20(9): e3001599, 2022.
Full-Text Article
[ Journal Article ]

SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis

Parthibane V, Lin J, Acharya D, Abimannan T, Srideshikan SM, Klarmann K, Yang A, Soheilian F, Nagashima K, Fox SD, Andresson T, Tessarollo L, Keller JR, Acharya U, Acharya JK
Journal of Biological Chemistry. 2021.
Full-Text Article
[ Journal Article ]

Sptlc1 Is Essential for Myeloid Differentiation and Hematopoietic Homeostasis

Parthibane V , Acharya D , Srideshikan SM, Lin J, Myerscough DG , Abimannan T, Vijaykrishna N, Blankenberg D, Bondada L, Klarmann KD, Fox SD, Andresson T, Tessarollo T, Acharya U, Keller JR, Acharya JK
Blood Advances. 3 (22): 3635-3649, 2019. [ Journal Article ]

Job Vacancies

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Team

Thiru
Postdoctoral Fellow (Visiting)
Thiruvaimozhi Abimannan, Ph.D.
Abhi
Postdoctoral Fellow (Visiting)
Abhilasha Kandahalli Venkataranga Nayaka, Ph.D.
Jacob
Postbaccalaureate Fellow
Jacob Tantalla
Vishal
Postdoctoral Fellow (Visiting)
Vishal Kumar Gupta, Ph.D.

News

Learn more about CCR research advances, new discoveries and more
on our news section.

Alumni

Parthi
Velayoudame Parthibane, Ph.D
2013-2023
Research Fellow
Diwash Acharya, B.S.
Diwash Acharya, B.S.
2009 - 2012
Postbaccalaureate Fellow (ORISE/NCI)
Prateek Paul
Prateek Paul
2014
Werner H. Kirsten Student Intern
Hirsh Shah
Hirsh Shah
2014
Werner H. Kirsten Student Intern
Abhishek Kapoor
Abhishek Kapoor
2014
Werner H. Kirsten Student Intern
Jing-Jing Ma, Ph.D.
Jing-Jing Ma, Ph.D.
2009 - 2013
Postdoctoral Fellow
Anish Gonchigar, B.S.
Anish Gonchigar, B.S.
2013
Postbaccalaureate Fellow
Razi Raziuddin, Ph.D.
Razi Raziuddin, Ph.D.
2012
Biologist
Meena Sharma, B.S.
Meena Sharma, B.S.
2011 - 2012
Postbaccalaureate Fellow
Rohan Hangal
Rohan Hangal
2012
Summer Student
Surabhi Rao
Surabhi Rao
2012
Summer Student
Zachary Daar
Zachary Daar
2012
Werner H. Kirsten Student Intern
Yasmin Lachir
Yasmin Lachir
2012
Werner H. Kirsten Student Intern
Shelby Payne
Shelby Payne
2012
Werner H. Kirsten Student Intern
Odilia Sendze
Odilia Sendze
2012
Werner H. Kirsten Student Intern
Rishabh Sharan
Rishabh Sharan
2012
Werner H. Kirsten Student Intern
Pralhada Rao Raghavendra
Pralhada Rao Raghavendra, Ph.D.
2005 - 2011
Research Fellow
Luanna Scheffer, Ph.D.
Luana Scheffer, Ph.D.
2010 - 2011
Postdoctoral Fellow
Priyanka Maskikar
Priyanka Maskikar
2011
Special Volunteer
Abid R. Mattoo, Ph.D.
Abid R. Mattoo, Ph.D.
2009 - 2010
Postdoctoral Fellow