Highlighted Publications

Highlighted research publications by our members are shown below.

2025

2024

• HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA

  
  Capoferri AA, Wiegand A, Hong F, Jacobs JL, Spindler J, Musick A, Bale MJ, Shao W, Sobolewski MD, Cillo AR, Luke BT, Fennessey CM, Gorelick RJ, Hoh R, Halvas EK, Deeks SG, Coffin JM, Mellors JW, Kearney MF.  Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2405210121.

• HIV-1 uncoating requires long double-stranded reverse transcription products

  
  Burdick RC, Morse M, Rouzina I, Williams MC, Hu WS, Pathak VK. Sci Adv. 2024 Apr 26;10(17):eadn7033.

• Complete Rescue of HTLV-1_p12KO Infectivity by Depletion of Monocytes Together with NK and CD8⁺ T Cells

  
  Gutowska A, Sarkis S, Rahman MA, Goldfarbmuren KC, Moles R, Bissa M, Doster M, Washington-Parks R, McKinnon K, Silva de Castro I, Schifanella L, Franchini G, Pise-Masison CA. Pathogens. 2024 Mar 29;13(4):292.

• Epistatic pathways can drive HIV-1 escape from integrase strand transfer inhibitors

  
  Hikichi Y, Grover JR, Schäfer A, Mothes W, Freed EO. Sci Adv. 2024  Mar;10(9): eadn0042.

• Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models

  
  Hogan CH, Owens SM, Reynoso GV, Liao Y, Meyer TJ, Zelazowska MA, Liu B, Li X, Grosskopf AK, Khairallah C, Kirillov V, Reich NC, Sheridan BS, McBride KM, Gewurz BE, Hickman HD, Forrest JC, Krug LT.  2024. mBio 15:e02998-23.

• Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

  
  Shi G, Li T, Lai KK, Johnson RF, Yewdell JW, Compton AA. Nat Commun. 2024 Jan 30;15(1):889.

2023

• RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules

  
  Majerciak V, Zhou T, Kruhlak MJ, Zheng ZM. Nucleic Acids Res. 2023 Sep 22;51(17):9337-9355.

• Potent dual block to HIV-1 infection using lentiviral vectors expressing fusion inhibitor peptide mC46- and Vif-resistant APOBEC3G

  
  Delviks-Frankenberry KA, Ojha CR, Hermann KJ, Hu WS, Torbett BE, Pathak VK. Mol Ther Nucleic Acids. 2023 Aug 11;33:794-809.

• HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness

  
  Nikolaitchik OA, Islam S, Kitzrow JP, Duchon A, Cheng Z, Liu Y, Rawson JMO, Shao W, Nikolaitchik M, Kearney MF, Maldarelli F, Musier-Forsyth K, Pathak VK, Hu WS. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2305103120.

• A virus-induced circular RNA maintains latent infection of Kaposi's sarcoma herpesvirus

  
  Tagawa T, Oh D, Dremel S, Mahesh G, Koparde VN, Duncan G, Andresson T, Ziegelbauer JM. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2212864120.