Clinical trial researching T-cell therapy for sarcoma

image of female physician using a stethoscope on a young female patient

Image credit: Canva

Soft tissue makes up many parts of the body, such as muscle, fat, tendons, ligaments and blood vessels. Cancers, such as sarcomas, can occur in these soft tissues, and researchers are constantly searching for possible treatment methods. John W. Glod, M.D., Ph.D., Associate Research Physician in the Pediatric Oncology Branch, is leading NCI’s participation in a clinical trial researching T-cell therapy for synovial sarcoma in children and young adults. The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.

For more information, please contact Jo Hurtt at (240) 858-7012 or identifier: NCT04044768

NCI Protocol ID: NCI-21-C-0022

Official Title: A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR™ T Cells in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.  

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Posted on Wed, 09/28/2022