We offer one fully funded postdoctoral position up to five years in the Laboratory of Genome Integrity located at the Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH). NIH is the largest biomedical research agency in the world, fosters world-renowned researchers and provides access to state-of-the art innovative technologies and scientific resources.
Our laboratory uses human and mouse embryonic stem cells, as well as mouse embryos to understand the molecular mechanisms underlying cell fate decisions. The applicant will be involved in a very exciting project investigating the relation between cell plasticity/totipotency and chromatin architecture (see our last publication about this topic, https://www.nature.com/articles/s41467-021-25072-x). We seek a highly motivated, creative individual, eager to learn and develop new technologies and complex cell systems based on live cell/embryo imaging, single-cell technologies and CRISPR-based editing who is interested in understanding how a single cell can develop into a complex multicellular organism in vitro and in vivo.
Qualifications and Job Details
Required and Preferred Skills
Applicants should have or about to have a Ph.D. in Developmental Biology, Genetics, Molecular Biology or similar, and must have demonstrated expertise on molecular biology/mammalian cell culture (preferably in embryonic stem cells). Knowledge in mouse embryology, single-cell RNAseq, chromatin architecture and/or next generation sequencing technologies will be considered as an advantage.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.