Brad Wood, M.D.
Dr. Bradford Wood directs a multi-disciplinary team at the NIH Center for Interventional Oncology that develops and translates devices, software and navigation approaches for cancer patients via novel local and regional minimally-invasive image-guided therapies.
At CCR, Dr. Wood serves in the Urologic Oncology Branch's clinical core and is also a member of the NCI CCR Liver Cancer Program.
1) navigation tools for local and regional tumor ablation and embolization, 2) local drug
delivery with micro- and nano-carriers, 3) fusion interventions, medical-GPS, or multi-modality, image-guided procedures, 4) biomedical imaging and biomedical engineering,
5) immuno-modulation with local and regional therapies in interventional oncology,
6) hepatocellular carcinoma
Dr. Wood is Director of the NIH Center for Interventional Oncology, which has been a partnership between the National Cancer Institute and the NIH Clinical Center for well over a decade. The Center translates technologies and paradigms for first in human treatments for cancer and cultivates interventional radiology applications within a muliti-disciplinary framework, to apply biomedical engineering to solve real-life clinical problems and patient care needs. Dr. Wood also serves as Chief, Interventional Radiology, NIH Clinical Center.
His team’s achievements include helping to pioneer several technologies from concept to bench to patient. The team was “first -in-human” for the following device/drug combinations: prostate cancer MRI/TRUS fusion biopsy and ablation, image-able iodinated drug eluting beads for chemoembolization of liver tumors, heat deployed chemotherapy combined with thermal ablation for liver cancer, “medical GPS” electromagnetic (EM) tracking for fusion of ultrasound to CT, MR, and PET, and fusion for needle-based procedures like biopsy and thermal ablation, and kidney and adrenal tumor ablation. The NIH team has performed over 40,000 needle procedures in over 2,500 patients with tracking and fusion technology, which has become a standard of care worldwide. The NCI CCR liver cancer team was also the first to combine check point immunotherapies with local and regional image-guided thermal ablation or chemo-embolization for liver and biliary tract cancers in clinical trials.
View Dr. Wood's Complete Bibliography at ResearcherID
Selected Recent Publications
Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer.JAMA. 313(4): 390-397, 2015. [ Journal Article ]
- Cardiovasc Intervent Radiol. 39(8): 1177-86, 2016. [ Journal Article ]
- J Hepatol. Epub ahead of print, 2019. [ Journal Article ]
Mapping Drug Dose Distribution on CT Images Following Transarterial Chemoembolization with Radiopaque Drug-Eluting Beads in a Rabbit Tumor Model.Radiology. 289(2): 396-404, 2018. [ Journal Article ]
Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma.Curr Oncol. 20(3): e274-7, 2013. [ Journal Article ]
Dr. Wood earned his B.A. and M.D. degrees from The University of Virginia, then did an Internal Medicine internship, followed by a Residency in Diagnostic Radiology at Georgetown University, where he was Chief Resident. He then went on to do double fellowships at Harvard/Massachusetts General Hospital (MGH) in Abdominal Imaging and Intervention and Vascular and Interventional Radiology, and stayed on staff at MGH after training.
Dr. Wood came to the NIH in 1998. He is the Chief of Interventional Radiology and the founding Director of the NIH Center for Interventional Oncology. He holds appointments in Radiology and Imaging Sciences in the Clinical Center, as well as the National Cancer Institute and the Urologic Oncology Branch in the NCI's Center for Cancer Research. He is the co-Program Director for the National Institute of Biomedical Imaging and Bioengineering (NIBIB) Clinical Translational Research Fellowship Program and a member of the NCI CCR Liver Cancer Program. He is a Fellow of the Society for Interventional Radiology and was Acting Co-Director of Radiology from 2006 to 2008.
His research relies upon multi-disciplinary team science within multiple institutes and international public-private partnerships. He has received the NIH Directors Award, the Clinical Center Director’s Award, the NCI Director’s Award of Merit, NCI Research Highlights Award, and the NIH Clinical Center CEO Award
Dr Wood has mentored hundreds of students, fellows, physicians, nurses, and scientists. He has published more than 10 issued patents, books on radiology and interventional urology, and co-authored more than 450 peer-reviewed manuscripts - (JAMA, Lancet, Science, Nature Reviews, Cancer, Blood, Chest, Transplantation, JAMA Oncology, Hepatology, CA: A Cancer Journal for Clinicians, Journal of Clinical Oncology, Medical Physics, Radiology, and Clinical Cancer Research.
He is most thankful for his stellar team who enable multidisciplinary team science.
|Victoria Anderson M.S.||Lead Nurse Practitioner (NIH Clinical Center)|
|John Karanian Ph.D.||Staff Scientist (NIH Clinical Center)|
|Elliot Levy M.D.||Staff Scientist (NIH Clinical Center)|
|Bill Pritchard M.D.||Medical Officer (NIH Clinical Center)|
|Sheng Xu Ph.D.||Staff Scientist (NIH Clinical Center)|