
Scott M. Norberg, D.O.
- Center for Cancer Research
- National Cancer Institute
- Building 10, Room 3-3132
- Bethesda, MD 20892
- 240-858-3303
- scott.norberg@nih.gov
RESEARCH SUMMARY
Dr. Norberg researches the use of immunotherapy and cellular therapy for a variety of conditions including human papillomavirus-positive (HPV+) cancers and premalignant diseases caused by chronic HPV infection. His research focuses on understanding resistance to immunotherapy and cellular therapies and applying these treatment modalities to other conditions.
Areas of Expertise
Information for Patients
Learn more about our clinical trials and the highly specialized care teams that lead them.

Scott M. Norberg, D.O.
Clinical Trials
Research
Dr. Norberg conducts clinical research to develop T cell therapies for the treatment of patients with cancer and precancerous diseases. This includes conducting clinical trials using genetically engineered T cells to treat patients with advanced human papillomavirus (HPV) malignancies.
Publications
PRGN-2012 gene therapy in adults with recurrent respiratory papillomatosis: a pivotal phase 1/2 clinical trial
Adoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen spreading and elimination of antigen-negative tumor variants
The tumor microenvironment state associates with response to HPV therapeutic vaccination in patients with respiratory papillomatosis
Engineered T cell therapy for viral and non-viral epithelial cancers
Biography

Scott M. Norberg, D.O.
span data-style="font-size:14px;">Dr. Norberg received his B.S. from Saint Mary’s College of California and a M.S. in Medical Sciences at Drexel University. He received his medical degree at the Philadelphia College of Osteopathic Medicine. He completed his residency in internal medicine at Temple University Hospital and a fellowship in medical oncology at the National Cancer Institute. After fellowship training, he joined the research group of Dr. Christian Hinrichs where he conducts clinical research to develop T-cell therapies for patients with malignant and premalignant disease.
Dr. Norberg is board certified in internal medicine and medical oncology.