Wei Zhang, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 37, Room 1126
- Bethesda, MD 20892
Dr. Zhang's current research focuses on mechanistic and translational aspects of general and site-specific cancer metastasis. Specifically, he is interested in the mechanisms by which cancer cells and their microenvironments collectively contribute to the development of brain metastasis of breast cancer, with the ultimate goal of identifying molecules as the "liquid biopsy" for early diagnosis, and the targets for new preventives and therapies.
Areas of Expertise
1) blood-brain barrier 2) blood-tumor barrier 3) cancer epigenetics 4) tumor Immunology 5) liquid biopsy 6) human papillomavirus (HPV)
Selected Recent Publications
Itraconazole Exerts Its Antitumor Effect in Esophageal Cancer by Suppressing the HER2/AKT Signaling Pathway
Mol Cancer Ther. 20(10): 1904-1915, 2021.
A "Clue" to Improving Liquid Biopsies for Cancer: Microfluidic Multiparametric Exosome Analysis
Clin Chem. 67(2): 335-337, 2021. [ Journal Article ]
Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett's Cells
Gastroenterology. 156(1): 130-144, 2019. [ Journal Article ]
KLF13 regulates the differentiation-dependent human papollomavirus life cycle in keratinocytes through STAT5 and IL-8
Oncogene. 35(42): 5565-5575, 2016. [ Journal Article ]