Swati S. Choksi, Ph.D.

Swati S. Choksi, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Swati Choksi is a Staff Scientist in the Laboratory of Immune Cell Biology at the National Cancer Institute, NIH. She is interested in cell death and the fine balance of apoptosis, necrosis and autophagy that regulates the fate of a cell. Her current work is focused on connecting cell death pathways to tumorigenesis.

Areas of Expertise

TNF Signaling
Mouse Tumor Models


Selected Recent Publications

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG.
Nat Cell Biol. 16: 55-65, 2014. [ Journal Article ]

ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

Zhang Y, Choksi S, Chen K, Pobezinskaya Y, Linnoila I, Liu ZG.
Cell Res. 23: 898-914, 2013. [ Journal Article ]

Induction of autophagy is essential for monocyte-macrophage differentiation

Zhang Y, Morgan MJ, Chen K, Choksi S, Liu ZG.
Blood. 119: 2895-905, 2012. [ Journal Article ]

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG.
Proc. Natl. Acad. Sci. U.S.A.. 109: 5322-7, 2012. [ Journal Article ]