Nadim  Majdalani, Ph.D.

Nadim Majdalani, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
  • Bldg.37, Room 5132
  • Bethesda, MD 20892-4264
  • 301-451-8788


The lab is focused on the role that small trans-acting RNAs do in helping the bacterium E. coli respond to stresses or changes in its environment. In particular, we have been interested in the physiological conditions under which the small RNAs become expressed and what mRNAs they target.

Areas of Expertise



Selected Publications

Adenovirus with hexon Tat-protein transduction domain modification exhibits increased therapeutic effect in experimental neuroblastoma and neuroendocrine tumors

Yu D, Jin C, Leja J, Majdalani N, Nilsson B, Eriksson F, Essand M.
J. Virol.. 85: 13114-23, 2011. [ Journal Article ]

H-NS regulation of IraD and IraM antiadaptors for control of RpoS degradation

Battesti A, Tsegaye YM, Packer DG, Majdalani N, Gottesman S.
J. Bacteriol.. 194: 2470-8, 2012. [ Journal Article ]

The RpoS-mediated general stress response in Escherichia coli

Battesti A, Majdalani N, Gottesman S.
Annu. Rev. Microbiol.. 65: 189-213, 2011. [ Journal Article ]

Production of recombinant protein by a novel oxygen-induced system in Escherichia coli

Baez A, Majdalani N, Shiloach J.
Microb. Cell Fact.. 13: 50, 2014. [ Journal Article ]

Reducing acetate excretion from E. coli K-12 by over-expressing the small RNA SgrS

Negrete A, Majdalani N, Phue JN, Shiloach J.
N Biotechnol. 30: 269-73, 2013. [ Journal Article ]