Headshot of Michael Lichten

Michael Lichten, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Lichten has made seminal contributions to understanding the mechanisms and regulation of homologous recombination during meiosis. His research used budding yeast as a model system, to study mechanisms that protect and maintain genome integrity.

Areas of Expertise

Homologous Recombination
DNA Repair
Chromosome Structure
Saccharomyces Cerevisiae


Selected Recent Publications

Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination

Ahuja JS, Harvey CS, Wheeler DL, LichtenM.
Molecular Cell. 81: 4258-4270, 2021.
Full-Text Article
[ Journal Article ]

Unresolved Recombination Intermediates Cause a RAD9-Dependent Cell Cycle Arrest in Saccharomyces cerevisiae

Kaur H, Gn K, Lichten M.
Genetics. 213(3): 805-818, 2019. [ Journal Article ]

Noncanonical Contributions of MutLγ to VDE-Initiated Crossovers During Saccharomyces cerevisiae Meiosis

Anura Shodhan
Darpan Medhi
Michael Lichten
G3 Genes|Genomes|Genetics. 9: 1647-1654, 2019.
Full-Text Article

Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis

Medhi D, Goldman AS, Lichten M.
eLife. 5: e19669, 2016. [ Journal Article ]