Lin Zhang, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 37, Room 3044
- Bethesda, MD 20892
- Lin.Zhang@nih.gov
RESEARCH SUMMARY
Lin got his PhD degree from Shanghai Jiao Tong University, Shanghai, China. His previous research focused mainly on transcriptional regulation of the cancer stem cell marker CD133 and the function of MORC2/PAPR1 in DNA damage.
Areas of Expertise
Lin Zhang, Ph.D.
Biography
Lin Zhang, Ph.D.
Biography:
Lin received his Ph.D. degree from Shanghai Jiao Tong University in 2014. During his Ph. D. studies, Lin focused on the transcriptional regulation of CD133 in hepatocellular carcinoma (HCC). After graduation, he studied the crosstalk between MORC2 and PARP1 in DNA damage response at Fudan University Shanghai Cancer Center. He started working at the Laboratory of human carcinogenesis in Dr. Hussain`s lab as a postdoc in 2019. His current research focuses on the metastasis and microenvironment of pancreatic cancer.
Publications
- Inhibitory effects of transcription factor Ikaros on the expression of liver ca…
- CXCL3 contributes to CD133(+) CSCs maintenance and forms a positive feedback re…
- MORC2 regulates DNA damage response through a PARP1-dependent pathway
- Stabilization of MORC2 by estrogen and antiestrogens through GPER1- PRKACA-CMA …
- Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resis…