Kaska Wloka, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 10, Room B1B42
- Bethesda, MD 20892
Dr. Wloka heads the Clinical Research Correlatives Core, which provides full flow cytometry service to the CCR’s clinical investigators, including development of state-of-the-art spectral flow-based assays for evaluation of clinical protocol endpoints and research correlatives.
Areas of Expertise
1) immunology, 2) spectral flow cytometry 3) immunophenotyping 4) inflammation 5) leukocyte migration
Dr. Wloka and her team are developing new strategies using multiparametric, spectral flow cytometry to study and characterize:
- phenotype and cellular microenvironment of various hematologic and solid neoplasms (with the goal of identifying novel therapeutic targets)
- phenotypic changes in adoptively transferred immune cells (CAR-T cells) post infusion (monitoring of adoptive immunotherapy)
- effect of different therapeutic modalities on engraftment and immune reconstitution after hematopoietic stem-cell transplantation
Topical glucocorticoid therapy directly induces up-regulation of functional CXCR4 on primed T lymphocytes in the aqueous humor of patients with uveitis
Kaska Wloka, Ph.D.
Kaska Wloka, received her B.Sc.(Hns) in Immunology from University of Glasgow, Scotland and her Ph.D. in immunology from the Medical Research Council Center for Immune Regulation, University of Birmingham, England. She completed her postdoctoral training at the NIAID and NIDCR, after which she joined Dr. Rachel Caspi’s laboratory at NEI/NIH to pursue her research interests in ocular immunology. Dr. Wloka joined the Laboratory of Pathology in 2020 and is now heading the Clinical Research Correlatives Core, assisting CCR investigators with her expertise in spectral flow cytometry technology and cellular immunology.
Dr. Wloka is a member of the American Association of Immunologists, International Society for Advancement of Cytometry and International Clinical Cytometry Society.