Izumi Horikawa, M.D., Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Bldg 37, Rm 3054
- Bethesda, MD 20892
- 240-760-7775
- horikawi@mail.nih.gov
Staff Scientist
RESEARCH SUMMARY
Dr. Horikawa focuses on cancer and aging research, with a special interest in telomeres, cellular senescence, microRNA and p53.Areas of Expertise
Telomeres
MicroRNA
Izumi Horikawa, M.D., Ph.D.
Research
Cancer and aging research, with special interest in telomeres, cellular senescence, microRNA and p53
Publications
Selected Recent Publications
Radiation-induced astrocyte senescence is rescued by Δ133p53
Neuro Oncol.
21(4):
474-485,
2019.
[ Journal Article ]
Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells
Cell Death Dis.
9(7):
750,
2018.
[ Journal Article ]
p53 isoforms regulate premature aging in human cells
Oncogene.
37(18):
2379-2393,
2018.
[ Journal Article ]
Δ133p53: A p53 isoform enriched in human pluripotent stem cells
Cell Cycle.
16(18):
1631-1632,
2017.
[ Journal Article ]
Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells
Cell Death Differ.
24(6):
1017-1028,
2017.
[ Journal Article ]
Biography
Staff Scientist
Izumi Horikawa, M.D., Ph.D.
1995 Postdoctoral fellow, NIEHS, Research Triangle Park, NC 1999 Research fellow, NIEHS, Research Triangle Park, NC 2002 Staff Scientist, CCR, NCI, Bethesda, MD