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Dunrui Wang, Ph.D.

Dunrui Wang Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

Dr. Wang's research interests include bringing insights into cancer by applying and developing solutions for the analysis of tumor genomic and proteomic datasets. He has used his bioinformatic and data analytical skills to collaborate with researchers both within and outside of the NIH.

Areas of Expertise

Bioinformatics
Genomic And Proteomic Data Analysis
Cancer Biology

Publications

Selected Recent Publications

High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer

Lin A, Feng J, Chen X, Wang D, Wong M, Zhang G, Na J, Zhang T, Chen Z, Chen YT, Du YC.
Cancer Letters. 514: 79-89, 2021. [ Journal Article ]

Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth

Wang Y, Salvucci O, Ohnuki H, Tran AD., Ha T, Feng, JX, DiPrima M, Kwak H, Wang D, Yu Y, Kruhlak M, Tosato G.
EMBO Molecular Medicine. 13: 14089, 2021. [ Journal Article ]

Cancer-associated point mutations in the DLC1 tumor suppressor and other Rho-GAPs occur frequently and are associated with decreased function

Wang D, Qian X, Sanchez-Solana B, Tripathi BK, Durkin EM, Lowy DR.
Cancer Research. 80: 3564-3579, 2020. [ Journal Article ]

Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma

DiPrima M, Wang D, TrÖster A, Maric D, Terrades-Garcia N, Ha T, Kwak H, Sanchez-Martin D, Kudlinzki D, Schwalbe H, Tosato, G.
Molecular Oncology. 13: 2441-2459, 2019. [ Journal Article ]

SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor function

Tripathi BK, Anderman M, Qian X, Zhou M, Wang D, Papageorge AG, Lowy DR.

Journal of Cell Biology. 218: 3060-3076, 2019. [ Journal Article ]