Aleksandra Michalowska, PhD, MSc
- Center for Cancer Research
- National Cancer Institute
- Building 37, Room 3134B
- Bethesda, MD 20892
- 240-760-6938
- MichaloA@mail.nih.gov
RESEARCH SUMMARY
Dr. Michalowska is a bioinformatics scientist specializing in computational and statistical approaches for preclinical cancer research. Her work integrates multi-omics data, including single-cell and spatial transcriptomics, to elucidate molecular mechanisms driving cancer progression and therapeutic response. She develops analytical frameworks to interpret large-scale transcriptional signatures from patient samples and experimental models while designing scalable workflows for next-generation sequencing and multimodal data integration, facilitating the discovery of predictive biomarkers and advancing precision oncology. Moreover, she specializes in high-throughput drug screening, utilizing advanced screening platforms and analytical methods to optimize both single-agent and combination treatment strategies for cancer therapy development.
Areas of Expertise
Aleksandra Michalowska, PhD, MSc
Research
Dr. Michalowska is a bioinformatics scientist specializing in computational and statistical approaches for preclinical cancer research. Her work integrates multi-omics data, including single-cell and spatial transcriptomics, to elucidate molecular mechanisms driving cancer progression and therapeutic response. She develops analytical frameworks to interpret large-scale transcriptional signatures from patient samples and experimental models while designing scalable workflows for next-generation sequencing and multimodal data integration, facilitating the discovery of predictive biomarkers and advancing precision oncology. Moreover, she specializes in high-throughput drug screening, utilizing advanced screening platforms and analytical methods to optimize both single-agent and combination treatment strategies for cancer therapy development.
Dr. Michalowska conducts collaborative research within the Laboratory of Cancer Biology and Genetics and the National Center for Advancing Translational Sciences (NCATS) at NIH.
Inventions: Gene expression signatures of neoplasm responsiveness to therapy. US Patent Application 20140357660.
Publications
Biography
Aleksandra Michalowska, PhD, MSc
Dr. Aleksandra Michalowska received her M.Sc. and Ph.D. in biological sciences from Adam Mickiewicz University (UAM) in Poznań, Poland. She completed her postdoctoral training under Dr. Richard Simon at the Biometric Research Branch, Division of Cancer Treatment and Diagnosis, NCI, where she conducted research focusing on statistical analysis and computational programming in cancer genomics. Dr. Michalowska joined the Laboratory of Cancer Biology and Genetics in 2005 as a Research Fellow and was promoted to the position of Staff Scientist in 2011.