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Clinical trial researching therapy for some small cell lung cancers

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Small cell lung cancers account for approximately 15 percent of cancers that begin in the tissue that lines or covers the airways of the lungs. Anish Thomas, M.B.B.S., M.D., Lasker Clinical Research Scholar in the Developmental Therapeutics Branch, is leading NCI’s participation in a clinical trial researching combination drug treatments for these cancers. The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.

For more information, please contact Linda Sciuto at (240) 760-6117 or linda.sciuto@nih.gov

Clinicaltrials.gov identifier: NCT04768296

NCI Protocol ID: NCI000288

Official Title: A Phase II, Open-label, Single-arm Study of Berzosertib (M6620) in Combination With Topotecan in Participants With Relapsed Platinum-resistant Small-Cell Lung Cancer (DDRiver SCLC 250)

The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.  

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Posted on Tue, 04/26/2022