Clinical trial researches CAR T-cell therapy for B-cell cancers

Male doctor with female patient

Image credit: Canva

B-cell leukemias and lymphomas are cancers that affect B-cells, a type of white blood cell of the immune system. A clinical trial led by James N. Kochenderfer, M.D., Senior Investigator in the Surgery Branch, is researching CAR T-cell therapy, which uses a patient’s own immune cells that are modified to carry genes that can kill cancer cells, against these types of cancers.  

The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.

For more information, contact Genevieve C. Fromm at (240) 858-3663 or identifier: NCT05797233

NCI Protocol ID: IRB001524

Official Title: A Phase I Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T- Cells for Treating B-cell Malignancies

The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.  

For more information on CCR clinical trials click here, and subscribe to have the latest CCR clinical trials sent directly to your inbox.

Posted on Thu, 09/14/2023