Members of the Myeloid Malignancies Program regularly publish in peer-reviewed journals. You can find a selection of our most recent papers below (Updated 12/16/2024).
Systemic Treatment with the Janus Kinase Inhibitor Baricitinib in Ocular Chronic Graft-versus-Host Disease
McManus T, Holtzman NG, Zhao A, Cousineau-Krieger C, Vitale S, FitzGibbon EJ, Payne D, Newgen J, Igbinosun C, Im AP, Peer C, Figg WD, Sr., Cowen EW, Mays JW, Pavletic S, Magone MT
Ophthalmol Sci 2025 5(1): 100627 Jan-Feb
A Call to Arms: Overcoming challenges in Myelodysplastic Syndromes therapy advances
McGraw KL, Aplan PD, Pavletic SZ
Semin Hematol 2024 61(6): 345-347 Dec
Targeted therapy in acute T-cell leukemia/lymphoma: are we close?
Mina A
Leuk Lymphoma 2024 1-3 Dec 1
Implications for metabolic disturbances in myelodysplastic syndromes
McGraw KL, Larson DR
Semin Hematol 2024 Nov 22
Patient-reported outcomes in early phase trials for patients with myelodysplastic syndromes
Mendoza T, King AL, Vera E, Mina A, McGraw K, Pavletic S, Armstrong TS
Seminars in Hematology 2024 Oct 30
Intestinal microbiome and myelodysplastic syndromes: Current state of knowledge and perspectives for future
Simunic M, McGraw K, Pavletic SZ, Rashidi A
Seminars in Hematology 2024 Oct 28
Allogeneic hematopoietic cell transplantation in elderly patients with myelodysplastic syndromes: Considerations and challenges
Schulz E, Pavletic SZ, Mina A
Seminars in Hematology 2024 Oct 17
Challenges and solutions for cellular therapy development in autoimmune diseases
Volkmann ER, Varga J, Blazar BR, Pavletic SZ
Lancet Rheumatol 2024 Sep 24
Hematopoietic Cell Transplantation for DOCK8 Deficiency: Results from a Prospective Clinical Trial
Freeman AF, Gonzalez CE, Yates B, Cole K, Little L, Flannelly E, Steinberg SM, Mo G, Piette N, Hughes TE, Cuellar-Rodriguez J, Gea-Banacloche J, Heller T, Hammoud DA, Holland SM, Kong HH, Young FD, Jing H, Kayaoglu B, Su HC, Pai SY, Hickstein DD, Shah NN
J Allergy Clin Immunol 2024 Sep 2
RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
Ben-Crentsil NA, Mohammed Ismail W, Balasis ME, Newman H, Quintana A, Binder M, Kruer T, Neupane S, Ferrall-Fairbanks MC, Fernandez J, Lasho TL, Finke CM, Ibrahim ML, McGraw KL, Wysota M, Aldrich AL, Ryder CB, Letson CT, Traina J, McLemore AF, Droin N, Shastri A, Yun S, Solary E, Sallman DA, Beg AA, Ma L, Gaspar-Maia A, Patnaik MM, Padron E
Cancer Discov 2024 Aug 27
Role of allogeneic hematopoietic cell transplantation in VEXAS syndrome
Dias AL, Groarke EM, Hickstein D, Patel B
Ann Hematol 2024 Aug 22
Breaking Boundaries: Immunotherapy for Myeloid Malignancies
Gavrilova T, Schulz E, Mina A
Cancers (Basel) 2024 16(16): Aug 6
Infections and antimicrobial prophylaxis in patients with myelodysplastic syndromes
Czech MM, Schulz E, Mina A, Gea-Banacloche J
Semin Hematol 2024 Aug 3
The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development
Bertoli RM, Chung YJ, Difilippantonio MJ, Wokasch A, Marasco MRB, Klimaszewski H, Gammell S, Zhu YJ, Walker RL, Cao D, Khanna A, Walter MJ, Doroshow JH, Meltzer PS, Aplan PD
Cancer Res 2024 84(15): 2518-2532 Aug 1
How I treat post-immunotherapy relapsed B-ALL
Lamble AJ, Kovach AE, Shah NN
Blood 2024 Jul 24
Safety and efficacy of immunosuppressive therapy for elderly patients with severe aplastic anaemia
Prabahran A, Durrani J, Coelho-Da Silva J, Shalhoub R, Lotter J, Rios O, Ritchie DS, Wu CO, Patel BA, Young NS, Groarke EM
Br J Haematol 2024 Jul 17
Real-Time Visualization of Spliceosome Assembly Reveals Basic Principles of Splice Site Selection
Donovan BT, Wang B, Garcia GR, Mount SM, Larson DR
bioRxiv 2024 Jul 13
Overcoming the challenges of primary resistance and relapse after CAR-T cell therapy
Dreyzin A, Rankin AW, Luciani K, Gavrilova T, Shah NN
Expert Rev Clin Immunol 2024 20(7): 745-763 Jul
Opportunistic Infections, Mortality Risk, and Prevention Strategies in Patients With Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome
Czech M, Cuellar-Rodriguez J, Patel BA, Groarke EM, Cowen EW, Turturice B, Beck DB, Wilson L, Goodspeed W, Darden I, Young NS, Hickstein D, Ombrello A, Hoffman P, Arikan EA, Sinaii N, Hathaway L, Castelo-Soccio L, Fike A, Kastner DB, Grayson PC, Ferrada MA
Open Forum Infect Dis 2024 11(7): ofae405 Jul
Venous and arterial thrombosis in patients with VEXAS syndrome
Kusne Y, Ghorbanzadeh A, Dulau-Florea A, Shalhoub R, Alcedo PE, Nghiem K, Ferrada MA, Hines A, Quinn KA, Panicker SR, Ombrello AK, Reichard K, Darden I, Goodspeed W, Durrani J, Wilson L, Olteanu H, Lasho T, Kastner DL, Warrington KJ, Mangaonkar A, Go RS, Braylan RC, Beck DB, Patnaik MM, Young NS, Calvo KR, Casanegra AI, Grayson PC, Koster MJ, Wu CO, Kanthi Y, Patel BA, Houghton DE, Groarke EM
Blood 2024 143(21): 2190-2200 May
How I reduce and treat posttransplant relapse of MDS
Mina A, Greenberg PL, Deeg HJ
Blood 2024 143(14): 1344-1354 Apr 4
The evolution of preclinical models for myelodysplastic neoplasms
Mina A, Pavletic S, Aplan PD
Leukemia 2024 38(4): 683-691 Apr
Persistent IDH mutations are not associated with increased relapse or death in patients with IDH-mutated acute myeloid leukemia undergoing allogeneic hematopoietic cell transplant with post-transplant cyclophosphamide
Ravindra N, Dillon LW, Gui G, Smith M, Gondek LP, Jones RJ, Corner A, Hourigan CS, Ambinder AJ
Bone Marrow Transplant 2024 59(3): 428-430 Mar
TP53 mutation screening for patients at risk of myeloid malignancy
Mukherjee D, Lawal RA, Fitzhugh CD, Hourigan CS, Dillon LW
medRxiv 2024 Feb 8
Quantification of measurable residual disease using duplex sequencing in adults with acute myeloid leukemia
Dillon LW, Higgins J, Nasif H, Othus M, Beppu L, Smith TH, Schmidt E, Valentine Iii CC, Salk JJ, Wood BL, Erba HP, Radich JP, Hourigan CS
Haematologica 2024 109(2): 401-410 Feb 1
Clonal Hematopoiesis, Inflammation, and Hematologic Malignancy
Kanagal-Shamanna R, Beck DB, Calvo KR
Annu Rev Pathol 2024 19(479-506 Jan 24
Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy
Yu K, Deuitch N, Merguerian M, Cunningham L, Davis J, Bresciani E, Diemer J, Andrews E, Young A, Donovan F, Sood R, Craft K, Chong S, Chandrasekharappa S, Mullikin J, Liu PP
Blood Adv 2024 8(2): 497-511 Jan 23
Red cell distribution width as a new prognostic biomarker in refractory chronic graft-versus-host disease
Schulz E, Pirsl F, Holtzman NG, Beshensky D, Cowen EW, Mitchell SA, Steinberg SM, Pavletic SZ
Haematologica 2024 109(1): 298-302 Jan 1
Test Then Erase? Current Status and Future Opportunities for Measurable Residual Disease Testing in Acute Myeloid Leukemia
Blackmon AL, Hourigan CS
Acta Haematol 2024 147(2): 133-146
5-Aza-4'-thio-2'-deoxycytidine induces C>G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia
Aplan P, Bertoli R, Chung YJ, Difilippantonio M, Wokasch A, Marasco M, Klimaszewski H, Garber S, Zhu Y, Walker R, Cao D, Doroshow J, Meltzer P
Res Sq 2023 Dec 19
When to consider inherited marrow failure syndromes in adults
Gutierrez-Rodrigues F, Patel BA, Groarke EM
Hematology Am Soc Hematol Educ Program 2023 2023(1): 548-555 Dec 8
Metabolic syndrome prevalence and impact on outcomes in patients with chronic graft-versus-host disease
Zhao AT, Pirsl F, Steinberg SM, Holtzman NG, Schulz E, Mina A, Mays JW, Cowen EW, Comis LE, Joe GO, Yanovski JA, Pavletic SZ
Bone Marrow Transplant 2023 58(12): 1377-1383 Dec
Germline Predisposition to Myeloid Neoplasms: Diagnostic Concepts and Classifications
Obiorah IE, Upadhyaya KD, Calvo KR
Clin Lab Med 2023 43(4): 615-638 Dec
Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis
Murthy HS, Zhang MJ, Chen K, Ahmed S, Deotare U, Ganguly S, Kansagra A, Michelis FV, Nishihori T, Patnaik M, Abid MB, Aljurf M, Arai Y, Bacher U, Badar T, Badawy SM, Ballen K, Battiwalla M, Beitinjaneh A, Bejanyan N, Bhatt VR, Brown VI, Martino R, Cahn JY, Castillo P, Cerny J, Chhabra S, Copelan E, Daly A, Dholaria B, Diaz Perez MA, Freytes CO, Grunwald MR, Hashmi S, Hildebrandt GC, Jamy O, Joseph J, Kanakry CG, Khera N, Krem MM, Kuwatsuka Y, Lazarus HM, Lekakis LJ, Liu H, Modi D, Munshi PN, Mussetti A, Palmisiano N, Patel SS, Rizzieri DA, Seo S, Shah MV, Sharma A, Sohl M, Solomon SR, Ulrickson M, Ustun C, van der Poel M, Verdonck LF, Wagner JL, Wang T, Wirk B, Zeidan A, Litzow M, Kebriaei P, Hourigan CS, Weisdorf DJ, Saber W, Kharfan-Dabaja MA
Blood Adv 2023 7(22): 7007-7016 Nov 28
KPT-8602 Induced Hematopoietic Differentiation in U2AF1 S34F Mutant Cells and Myelodysplastic Syndromes Bone Marrow Stem and Progenitor Cells
Galiano VV, Garcia G, Swoboda DM, McKinnon K, Larson D, McGraw KL
Blood 2023 142 Nov 2
Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS)
Stahl M, Bewersdorf JP, Xie Z, Porta MGD, Komrokji R, Xu ML, Abdel-Wahab O, Taylor J, Steensma DP, Starczynowski DT, Sekeres MA, Sanz G, Sallman DA, Roboz GJ, Platzbecker U, Patnaik MM, Padron E, Odenike O, Nimer SD, Nazha A, Majeti R, Loghavi S, Little RF, List AF, Kim TK, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Gore SD, Greenberg P, Figueroa ME, Fenaux P, Efficace F, DeZern AE, Daver NG, Churpek JE, Carraway HE, Buckstein R, Brunner AM, Boultwood J, Borate U, Bejar R, Bennett JM, Wei AH, Santini V, Savona MR, Zeidan AM
Blood Rev 2023 62(101128) Nov
Predicted leukocyte telomere length and risk of myeloid neoplasms
Sullivan SM, Cole B, Lane J, Meredith JJ, Langer E, Hooten AJ, Roesler M, McGraw KL, Pankratz N, Poynter JN
Hum Mol Genet 2023 32(20): 2996-3005 Oct 4
How I diagnose myeloid neoplasms with germline predisposition
Patel N, Calvo KR
Am J Clin Pathol 2023 160(4): 352-364 Oct 3
Allogeneic Hematopoietic Cell Transplantation Improves Outcome in Myelodysplastic Syndrome Across High-Risk Genetic Subgroups: Genetic Analysis of the Blood and Marrow Transplant Clinical Trials Network 1102 Study
Versluis J, Saber W, Tsai HK, Gibson CJ, Dillon LW, Mishra A, McGuirk J, Maziarz RT, Westervelt P, Hegde P, Mukherjee D, Martens MJ, Logan B, Horowitz M, Hourigan CS, Nakamura R, Cutler C, Lindsley RC
J Clin Oncol 2023 41(28): 4497-4510 Oct 1
Management of Down Syndrome-Associated Leukemias: A Review
Verma A, Lupo PJ, Shah NN, Hitzler J, Rabin KR
JAMA Oncol 2023 9(9): 1283-1290 Sep 1
Prognostic impact of secondary versus de novo ontogeny in acute myeloid leukemia is accounted for by the European LeukemiaNet 2022 risk classification
Hochman MJ, Othus M, Hasserjian RP, Ambinder A, Brunner A, Percival MM, Hourigan CS, Swords R, DeZern AE, Estey EH, Karp JE
Leukemia 2023 37(9): 1915-1918 Sep
Moving toward a conceptualization of measurable residual disease in myelodysplastic syndromes
Schulz E, Aplan PD, Freeman SD, Pavletic SZ
Blood Adv 2023 7(16): 4381-4394 Aug 22
Persistent IDH mutations are not associated with increased relapse or death in patients with IDH-mutated acute myeloid leukemia undergoing allogeneic hematopoietic cell transplant with post-transplant cyclophosphamide
Ravindra N, Dillon LW, Gui G, Smith M, Gondek LP, Jones RJ, Corner A, Hourigan CS, Ambinder AJ
medRxiv 2023 Aug 21
Early activation of inflammatory pathways in UBA1-mutated hematopoietic stem and progenitor cells in VEXAS
Wu Z, Gao S, Gao Q, Patel BA, Groarke EM, Feng X, Manley AL, Li H, Ospina Cardona D, Kajigaya S, Alemu L, Quinones Raffo D, Ombrello AK, Ferrada MA, Grayson PC, Calvo KR, Kastner DL, Beck DB, Young NS
Cell Rep Med 2023 4(8): 101160 Aug 15
Measurable Residual IDH1 before Allogeneic Transplant for Acute Myeloid Leukemia
Gui G, Dillon LW, Ravindra N, Hegde PS, Andrew G, Mukherjee D, Wong Z, Auletta J, El Chaer F, Chen E, Chen YB, Corner A, Devine SM, Iyer S, Jimenez Jimenez AM, De Lima MJG, Litzow MR, Kebriaei P, Spellman SR, Zeger SL, Page KM, Hourigan CS
medRxiv 2023 Aug 1
Spectrum of clonal hematopoiesis in VEXAS syndrome
Gutierrez-Rodrigues F, Kusne Y, Fernandez J, Lasho T, Shalhoub R, Ma X, Alessi H, Finke C, Koster MJ, Mangaonkar A, Warrington KJ, Begna K, Xie Z, Ombrello AK, Viswanatha D, Ferrada M, Wilson L, Go R, Kourelis T, Reichard K, Olteanu H, Darden I, Hironaka D, Alemu L, Kajigaya S, Rosenzweig S, Calado RT, Groarke EM, Kastner DL, Calvo KR, Wu CO, Grayson PC, Young NS, Beck DB, Patel BA, Patnaik MM
Blood 2023 142(3): 244-259 Jul 20
DNA Sequencing in Adults With Acute Myeloid Leukemia to Detect Residual Disease Prior to Hematopoietic Cell Transplant-Reply
Gui G, Dillon LW, Hourigan CS
JAMA 2023 330(2): 190-191 Jul 11
Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1(st) International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS)
Bewersdorf JP, Xie Z, Bejar R, Borate U, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE, Daver NG, Porta MGD, DeZern AE, Fenaux P, Figueroa ME, Gore SD, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim TK, Komrokji R, Kuchroo VK, List AF, Loghavi S, Majeti R, Odenike O, Patnaik MM, Platzbecker U, Roboz GJ, Sallman DA, Santini V, Sanz G, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Xu ML, Savona MR, Wei AH, Zeidan AM
Blood Rev 2023 60(101072 Jul
NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia
Matsukawa T, Yin M, Nigam N, Negi V, Li L, Small D, Zhu YJ, Walker RL, Meltzer PS, Aplan PD
Leukemia 2023 37(7): 1545-1548 Jul
How I treat AML incorporating the updated classifications and guidelines
El Chaer F, Hourigan CS, Zeidan AM
Blood 2023 141(23): 2813-2823 Jun 8
Measurable residual disease in patients undergoing allogeneic transplant for acute myeloid leukemia
Wong ZC, Dillon LW, Hourigan CS
Best Pract Res Clin Haematol 2023 36(2): 101468 Jun
Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndromes: The Current Landscape and Future Directions
Sabile J, Pavletic S, Migdady Y
Cancer J 2023 29(3): 179-187 May-Jun 01
Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A
Gonzalez-Menendez P, Phadke I, Olive ME, Joly A, Papoin J, Yan H, Galtier J, Platon J, Kang SWS, McGraw KL, Daumur M, Pouzolles M, Kondo T, Boireau S, Paul F, Young DJ, Lamure S, Mirmira RG, Narla A, Cartron G, Dunbar CE, Boyer-Clavel M, Porat-Shliom N, Dardalhon V, Zimmermann VS, Sitbon M, Dever TE, Mohandas N, Da Costa L, Udeshi ND, Blanc L, Kinet S, Taylor N
Blood 2023 141(20): 2520-2536 May 18
Differential diagnosis of bone marrow failure syndromes guided by machine learning
Gutierrez-Rodrigues F, Munger E, Ma X, Groarke EM, Tang Y, Patel BA, Catto LFB, Cle DV, Niewisch MR, Alves-Paiva RM, Donaires FS, Pinto AL, Borges G, Santana BA, McReynolds LJ, Giri N, Altintas B, Fan X, Shalhoub R, Siwy CM, Diamond C, Raffo DQ, Craft K, Kajigaya S, Summers RM, Liu P, Cunningham L, Hickstein DD, Dunbar CE, Pasquini R, De Oliveira MM, Velloso E, Alter BP, Savage SA, Bonfim C, Wu CO, Calado RT, Young NS
Blood 2023 141(17): 2100-2113 Apr 27
Post-transcriptional polyadenylation site cleavage maintains 3'-end processing upon DNA damage
Sfaxi R, Biswas B, Boldina G, Cadix M, Servant N, Chen H, Larson DR, Dutertre M, Robert C, Vagner S
EMBO J 2023 42(7): e112358 Apr 3
Quantification of measurable residual disease using duplex sequencing in adults with acute myeloid leukemia
Dillon LW, Higgins J, Nasif H, Othus M, Beppu L, Smith TH, Schmidt E, Valentine CC, 3rd, Salk JJ, Wood BL, Erba HP, Radich JP, Hourigan CS
medRxiv 2023 Mar 27
Therapy-related Myeloid Neoplasms Following PARP Inhibitors-Letter
Batalini F, Mina LA, Mina A
Clin Cancer Res 2023 29(6): 1157 Mar 14
DNA Sequencing to Detect Residual Disease in Adults With Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant
Dillon LW, Gui G, Page KM, Ravindra N, Wong ZC, Andrew G, Mukherjee D, Zeger SL, El Chaer F, Spellman S, Howard A, Chen K, Auletta J, Devine SM, Jimenez Jimenez AM, De Lima MJG, Litzow MR, Kebriaei P, Saber W, Weisdorf DJ, Hourigan CS
Jama 2023 329(9): 745-755 Mar 7
Recurrent germline variant in ATM associated with familial myeloproliferative neoplasms
Braunstein EM, Imada E, Pasca S, Wang S, Chen H, Alba C, Hupalo DN, Wilkerson M, Dalgard CL, Ghannam J, Liu Y, Marchionni L, Moliterno A, Hourigan CS, Gondek LP
Leukemia 2023 37(3): 627-635 Mar
Allogeneic Blood or Marrow Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Acute Lymphoblastic Leukemia in Patients Age >/=55 Years
Webster JA, Reed M, Tsai HL, Ambinder A, Jain T, Dezern AE, Levis MJ, Showel MM, Prince GT, Hourigan CS, Gladstone DE, Bolanos-Meade J, Gondek LP, Ghiaur G, Dalton WB, Paul S, Fuchs EJ, Gocke CB, Ali SA, Huff CA, Borrello IM, Swinnen L, Wagner-Johnston N, Ambinder RF, Luznik L, Gojo I, Smith BD, Varadhan R, Jones RJ, Imus PH
Transplant Cell Ther 2023 29(3): 182 e181-182 e188 Mar
Absolute lymphocyte count recovery following initial acute myelogenous leukemia therapy: Implications for adoptive cell therapy
Molina JC, Li Y, Otto WR, Miller TP, Getz KD, McCoubrey C, Ramos M, Krause E, Cao L, Gramatges MM, Rabin K, Scheurer M, Elgarten CW, Myers RM, Seif AE, Fisher BT, Shah NN, Aplenc R
Pediatr Blood Cancer 2023 70(1): e30062 Jan
Prediction of HLA genotypes from single-cell transcriptome data
Solomon BD, Zheng H, Dillon LW, Goldman JD, Hourigan CS, Heath JR, Khatri P
Front Immunol 2023 14(1146826)
Editorial: Understanding leukemia biology using genome editing techniques
Jimenez-Morales S, Banerjee K, Saha N, Basu A, McGraw KL
Front Oncol 2023 13(1323584)
Pyroptosis Markers in Human Primary Specimens: Quantification of Intracellular ASC Specks by Imaging Flow Cytometry and Extracellular Oxidized Mitochondrial by ELISA
McLemore AF, Lage SL, Dominical VM, Rodrigues MA, McGraw KL
Methods Mol Biol 2023 2641(81-100)
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions
Shin TH, Zhou Y, Chen S, Cordes S, Grice MZ, Fan X, Lee BC, Aljanahi AA, Hong SG, Vaughan KL, Mattison JA, Kohama SG, Fabre MA, Uchida N, Demirci S, Corat MAF, Metais JY, Calvo KR, Buscarlet M, Natanson H, McGraw KL, List AF, Busque L, Tisdale JF, Vassiliou GS, Yu KR, Dunbar CE
Blood 2022 140(16): 1774-1789 Oct 20
Predictors of clonal evolution and myeloid neoplasia following immunosuppressive therapy in severe aplastic anemia
Groarke EM, Patel BA, Shalhoub R, Gutierrez-Rodrigues F, Desai P, Leuva H, Zaimoku Y, Paton C, Spitofsky N, Lotter J, Rios O, Childs RW, Young DJ, Dulau-Florea A, Dunbar CE, Calvo KR, Wu CO, Young NS
Leukemia 2022 36(9): 2328-2337 Sep
Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes
McLemore AF, Hou HA, Meyer BS, Lam NB, Ward GA, Aldrich AL, Rodrigues MA, Vedder A, Zhang L, Padron E, Vincelette ND, Sallman DA, Abdel-Wahab O, List AF, McGraw KL
JCI Insight 2022 7(15): Aug 8
CD70 CAR T cells in AML: Form follows function
Mirazee J, Shah NN
Cell Rep Med 2022 3(5): 100639 May 17
Dual pyroptotic biomarkers predict erythroid response in lower-risk non-del(5q) myelodysplastic syndromes treated with lenalidomide and recombinant erythropoietin
Wang C, McGraw KL, McLemore AF, Komrokji R, Basiorka AA, Al Ali N, Lancet JE, Padron E, Kosmider O, Fontenay M, Fenaux P, List AF, Sallman DA
Haematologica 2022 107(3): 737-739 Mar 1
Meaningful response criteria for myelodysplastic syndromes
Kim N, Pavletic S, Norsworthy KJ
Br J Haematol 2022 196(5): 1137-1148 Mar
MYC amplifies gene expression through global changes in transcription factor dynamics
Patange S, Ball DA, Wan Y, Karpova TS, Girvan M, Levens D, Larson DR
Cell Rep 2022 38(4): 110292 Jan 25
Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration
Pearson AD, Rossig C, Mackall C, Shah NN, Baruchel A, Reaman G, Ricafort R, Heenen D, Bassan A, Berntgen M, Bird N, Bleickardt E, Bouchkouj N, Bross P, Brownstein C, Cohen SB, de Rojas T, Ehrlich L, Fox E, Gottschalk S, Hanssens L, Hawkins DS, Horak ID, Taylor DH, Johnson C, Karres D, Ligas F, Ludwinski D, Mamonkin M, Marshall L, Masouleh BK, Matloub Y, Maude S, McDonough J, Minard-Colin V, Norga K, Nysom K, Pappo A, Pearce L, Pieters R, Pule M, Quintas-Cardama A, Richardson N, Schussler-Lenz M, Scobie N, Sersch MA, Smith MA, Sterba J, Tasian SK, Weigel B, Weiner SL, Zwaan CM, Lesa G, Vassal G
Eur J Cancer 2022 160(112-133 Jan
Donor source and post-transplantation cyclophosphamide influence outcome in allogeneic stem cell transplantation for GATA2 deficiency
Nichols-Vinueza DX, Parta M, Shah NN, Cuellar-Rodriguez JM, Bauer TR, Jr., West RR, Hsu AP, Calvo KR, Steinberg SM, Notarangelo LD, Holland SM, Hickstein DD
Br J Haematol 2022 196(1): 169-178 Jan
Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design
Qin H, Yang L, Chukinas JA, Shah N, Tarun S, Pouzolles M, Chien CD, Niswander LM, Welch AR, Taylor N, Tasian SK, Fry TJ
J Immunother Cancer 2021 9(9): Sep
Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection
Wan Y, Anastasakis DG, Rodriguez J, Palangat M, Gudla P, Zaki G, Tandon M, Pegoraro G, Chow CC, Hafner M, Larson DR
Cell 2021 184(11): 2878-2895 e2820 May 27
Hematopoietic Cell Transplantation and Outcomes Related to Human Papillomavirus Disease in GATA2 Deficiency
Parta M, Cole K, Avila D, Duncan L, Baird K, Schuver BB, Wilder J, Palmer C, Daub J, Hsu AP, Zerbe CS, Marciano BE, Cuellar-Rodriguez JM, Bauer TR, Nason M, Calvo KR, Merideth M, Stratton P, DeCherney A, Shah NN, Holland SM, Hickstein DD
Transplant Cell Ther 2021 27(5): 435 e431-435 e411 May
Venetoclax/decitabine for a pediatric patient with chronic myelomonocytic leukemia
Molina JC, Asare JM, Tuschong L, West RR, Calvo KR, Persky R, Boyce AM, Hammoud DA, Holland SM, Hickstein D, Shah NN
Pediatr Blood Cancer 2021 68(3): e28865 Mar
A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation
Qayed M, Ahn KW, Kitko CL, Johnson MH, Shah NN, Dvorak C, Mellgren K, Friend BD, Verneris MR, Leung W, Toporski J, Levine J, Chewning J, Wayne A, Kapoor U, Triplett B, Schultz KR, Yanik GA, Eapen M
Blood 2021 137(7): 983-993 Feb 18
Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome
Vicente A, Patel BA, Gutierrez-Rodrigues F, Groarke E, Giudice V, Lotter J, Feng X, Kajigaya S, Weinstein B, Barranta E, Olnes MJ, Parikh AR, Albitar M, Wu CO, Shalhoub R, Calvo KR, Townsley DM, Scheinberg P, Dunbar CE, Young NS, Winkler T
Haematologica 2020 105(12): 2785-2794 Dec 1
A New Standard in Graft-versus-Host Disease Prophylaxis? An Introduction to Blood and Marrow Transplant Clinical Trials Network 1703
DeFilipp Z, Burns LJ, Jaglowski SM, Leppin AL, Pavletic S, Waldman B, Weisdorf DJ, Wood WA, Khera N
Biol Blood Marrow Transplant 2020 26(12): e305-e308 Dec
Concurrent chronic lymphocytic leukemia/small lymphocytic lymphoma and hairy cell leukemia: clinical, pathologic and molecular features
Obiorah IE, Francischetti IMB, Wang HW, Ahn IE, Wang W, Raffeld M, Kreitman RJ, Wiestner A, Calvo KR
Leuk Lymphoma 2020 61(13): 3177-3187 Dec
Cryptosporidium infection in dedicator of cytokinesis 8 (DOCK 8) deficiency
Ben Yakov G, Sharma D, Cho MH, Shah NN, Hickstein D, Urban A, Darnell D, Kapuria D, Marko J, Kleiner DE, Hadigan CM, Danielson J, Ham H, Vittal A, Su HC, Freeman AF, Heller T
J Allergy Clin Immunol Pract 2020 8(10): 3663-3666 e3661 Nov-Dec
Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)
Flaherty KT, Gray RJ, Chen AP, Li S, McShane LM, Patton D, Hamilton SR, Williams PM, Iafrate AJ, Sklar J, Mitchell EP, Harris LN, Takebe N, Sims DJ, Coffey B, Fu T, Routbort M, Zwiebel JA, Rubinstein LV, Little RF, Arteaga CL, Comis R, Abrams JS, O'Dwyer PJ, Conley BA, team N-M
J Clin Oncol 2020 38(33): 3883-3894 Nov 20
Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas
Coyne GO, Kummar S, Meehan RS, Do K, Collins JM, Anderson L, Ishii K, Takebe N, Zlott J, Juwara L, Piekarz R, Streicher H, Sharon E, Rubinstein L, Voth AR, Lozier J, Dull AB, Wilsker D, Hinoue T, Laird PW, Ferry-Galow KV, Kinders RJ, Parchment RE, Doroshow JH, Chen AP
Oncotarget 2020 11(44): 3959-3971 Nov 3
Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories
Johnson KD, Conn DJ, Shishkova E, Katsumura KR, Liu P, Shen S, Ranheim EA, Kraus SG, Wang W, Calvo KR, Hsu AP, Holland SM, Coon JJ, Keles S, Bresnick EH
J Exp Med 2020 217(11): Nov 2
Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation
Akef A, McGraw K, Cappell SD, Larson DR
PLoS Biol 2020 18(11): e3000920 Nov
Myelodysplasia in the setting of paroxysmal nocturnal hemoglobinuria: Interpretation of blast percentage in a marrow with erythroid hyperplasia
Groarke EM, Patel BA, Dulau-Florea A, Maric I, Young NS, Calvo KR
EJHaem 2020 1(2): 404-405 Nov
Diagnostic approach to the evaluation of myeloid malignancies following CAR T-cell therapy in B-cell acute lymphoblastic leukemia
Mo G, Wang HW, Talleur AC, Shahani SA, Yates B, Shalabi H, Douvas MG, Calvo KR, Shern JF, Chaganti S, Patrick K, Song Y, Fry TJ, Wu X, Triplett BM, Khan J, Gardner RA, Shah NN
J Immunother Cancer 2020 8(2): Nov
Clinical and molecular consequences of fusion genes in myeloid malignancies
Matsukawa T, Aplan PD
Stem Cells 2020 38(11): 1366-1374 Nov
Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft-versus-host disease
Ljubas Kelecic D, Lelas A, Karas I, Desnica L, Vukic T, Sabol I, Vranesic Bender D, Serventi Seiwerth R, Peric Z, Durakovic N, Vitali Cepo D, Vrhovac R, Nemet D, Pavletic S, Pulanic D, Krznaric Z
J Cancer Res Clin Oncol 2020 146(11): 2967-2978 Nov
The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design
Flaherty KT, Gray R, Chen A, Li S, Patton D, Hamilton SR, Williams PM, Mitchell EP, Iafrate AJ, Sklar J, Harris LN, McShane LM, Rubinstein LV, Sims DJ, Routbort M, Coffey B, Fu T, Zwiebel JA, Little RF, Marinucci D, Catalano R, Magnan R, Kibbe W, Weil C, Tricoli JV, Alexander B, Kumar S, Schwartz GK, Meric-Bernstam F, Lih CJ, McCaskill-Stevens W, Caimi P, Takebe N, Datta V, Arteaga CL, Abrams JS, Comis R, O'Dwyer PJ, Conley BA, Team N-M
J Natl Cancer Inst 2020 112(10): 1021-1029 Oct 1
Transcriptional Decoding of Morphogen Gradients during Development
Garcia GR, Larson DR
Dev Cell 2020 54(6): 687-688 Sep 28
B cell deficiency in patients with relapsed and refractory acute myeloid leukemia
Goswami M, Lindblad KE, Ramraj R, Dagur PK, Thompson J, McCoy JP, Hourigan CS
Clin Hematol Int 2020 2(3): 125-128 Sep
American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults
Sekeres MA, Guyatt G, Abel G, Alibhai S, Altman JK, Buckstein R, Choe H, Desai P, Erba H, Hourigan CS, LeBlanc TW, Litzow M, MacEachern J, Michaelis LC, Mukherjee S, O'Dwyer K, Rosko A, Stone R, Agarwal A, Colunga-Lozano LE, Chang Y, Hao Q, Brignardello-Petersen R
Blood Adv 2020 4(15): 3528-3549 Aug 11
Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide
Im A, Rashidi A, Wang T, Hemmer M, MacMillan ML, Pidala J, Jagasia M, Pavletic S, Majhail NS, Weisdorf D, Abdel-Azim H, Agrawal V, Al-Homsi AS, Aljurf M, Askar M, Auletta JJ, Bashey A, Beitinjaneh A, Bhatt VR, Byrne M, Cahn JY, Cairo M, Castillo P, Cerny J, Chhabra S, Choe H, Ciurea S, Daly A, Perez MAD, Farhadfar N, Gadalla SM, Gale R, Ganguly S, Gergis U, Hanna R, Hematti P, Herzig R, Hildebrandt GC, Lad DP, Lee C, Lehmann L, Lekakis L, Kamble RT, Kharfan-Dabaja MA, Khandelwal P, Martino R, Murthy HS, Nishihori T, O'Brien TA, Olsson RF, Patel SS, Perales MA, Prestidge T, Qayed M, Romee R, Schoemans H, Seo S, Sharma A, Solh M, Strair R, Teshima T, Urbano-Ispizua A, Van der Poel M, Vij R, Wagner JL, William B, Wirk B, Yared JA, Spellman SR, Arora M, Hamilton BK
Biol Blood Marrow Transplant 2020 26(8): 1459-1468 Aug
Motor ability, function, and health-related quality of life as correlates of symptom burden in patients with sclerotic chronic graft-versus-host disease receiving imatinib mesylate
Rosenthal EA, Ho PS, Joe GO, Mitchell SA, Booher S, Pavletic SZ, Baird K, Cowen EW, Comis LE
Support Care Cancer 2020 28(8): 3679-3689 Aug
Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion
Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG
Nat Commun 2020 11(1): 3339 Jul 3
Calcinosis Cutis in the Setting of Chronic Skin Graft-Versus-Host Disease
Saardi KM, Rosenstein RK, Anadkat MJ, Micheletti RG, Schiffenbauer AI, Pavletic SZ, Cowen EW
JAMA Dermatol 2020 156(7): 814-817 Jul 1
Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency
Wu Z, Gao S, Diamond C, Kajigaya S, Chen J, Shi R, Palmer C, Hsu AP, Calvo KR, Hickstein DD, Holland SM, Young NS
Blood Adv 2020 4(12): 2656-2670 Jun 23
A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors
Stein MN, Goodin S, Gounder M, Gibbon D, Moss R, Portal D, Lindquist D, Zhao Y, Takebe N, Tan A, Aisner J, Lin H, Ready N, Mehnert JM
Invest New Drugs 2020 38(3): 855-865 Jun
Microtransplantation in older patients with AML: A pilot study of safety, efficacy and immunologic effects
Sung AD, Jauhari S, Siamakpour-Reihani S, Rao AV, Staats J, Chan C, Meyer E, Gadi VK, Nixon AB, Lyu J, Xie J, Bohannon L, Li Z, Hourigan CS, Dillon LW, Wong HY, Shelby R, Diehl L, de Castro C, LeBlanc T, Brander D, Erba H, Galal A, Stefanovic A, Chao N, Rizzieri DA
Am J Hematol 2020 95(6): 662-671 Jun
Subsequent neoplasms and late mortality in children undergoing allogeneic transplantation for nonmalignant diseases
Kahn JM, Brazauskas R, Tecca HR, Bo-Subait S, Buchbinder D, Battiwala M, Flowers MED, Savani BN, Phelan R, Broglie L, Abraham AA, Keating AK, Daly A, Wirk B, George B, Alter BP, Ustun C, Freytes CO, Beitinjaneh AM, Duncan C, Copelan E, Hildebrandt GC, Murthy HS, Lazarus HM, Auletta JJ, Myers KC, Williams KM, Page KM, Vrooman LM, Norkin M, Byrne M, Diaz MA, Kamani N, Bhatt NS, Rezvani A, Farhadfar N, Mehta PA, Hematti P, Shaw PJ, Kamble RT, Schears R, Olsson RF, Hayashi RJ, Gale RP, Mayo SJ, Chhabra S, Rotz SJ, Badawy SM, Ganguly S, Pavletic S, Nishihori T, Prestidge T, Agrawal V, Hogan WJ, Inamoto Y, Shaw BE, Satwani P
Blood Adv 2020 4(9): 2084-2094 May 12
Randomized Phase II Study of First-Line Cladribine With Concurrent or Delayed Rituximab in Patients With Hairy Cell Leukemia
Chihara D, Arons E, Stetler-Stevenson M, Yuan CM, Wang HW, Zhou H, Raffeld M, Xi L, Steinberg SM, Feurtado J, James L, Wilson W, Braylan RC, Calvo KR, Maric I, Dulau-Florea A, Kreitman RJ
J Clin Oncol 2020 38(14): 1527-1538 May 10
Metabolic reprogramming augments potency of human pSTAT3-inhibited iTregs to suppress alloreactivity
Walton K, Fernandez MR, Sagatys EM, Reff J, Kim J, Lee MC, Kiluk JV, Hui JYC, McKenna D, Jr., Hupp M, Forster C, Linden MA, Lawrence NJ, Lawrence HR, Pidala J, Pavletic SZ, Blazar BR, Sebti SM, Cleveland JL, Anasetti C, Betts BC
JCI Insight 2020 5(9): May 7
Quality of Life in Patients With Skin of Color and Chronic Graft-vs-Host Disease
Smith ZI, Rosenstein RK, Banerjee S, Pichard DC, Pavletic SZ, Cowen EW
JAMA Dermatol 2020 156(5): 589-590 May 1
Immune Response Following Quadrivalent Human Papillomavirus Vaccination in Women After Hematopoietic Allogeneic Stem Cell Transplant: A Nonrandomized Clinical Trial
Stratton P, Battiwalla M, Tian X, Abdelazim S, Baird K, Barrett AJ, Cantilena CR, Childs RW, DeJesus J, Fitzhugh C, Fowler D, Gea-Banacloche J, Gress RE, Hickstein D, Hsieh M, Ito S, Kemp TJ, Khachikyan I, Merideth MA, Pavletic SZ, Quint W, Schiffman M, Scrivani C, Shanis D, Shenoy AG, Struijk L, Tisdale JF, Wagner S, Williams KM, Yu Q, Wood LV, Pinto LA
JAMA Oncol 2020 6(5): 696-705 May 1
NCCN Guidelines: Pretransplant Recipient Evaluation and Management of Graft-Versus-Host Disease
Cutler C, Pavletic SZ
J Natl Compr Canc Netw 2020 18(5): 645-647 May
Statistics and measurable residual disease (MRD) testing: uses and abuses in hematopoietic cell transplantation
Othus M, Gale RP, Hourigan CS, Walter RB
Bone Marrow Transplant 2020 55(5): 843-850 May
Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias
Fan X, Desmond R, Winkler T, Young DJ, Dumitriu B, Townsley DM, Gutierrez-Rodrigues F, Lotter J, Valdez J, Sellers SE, Barranta ME, Shalhoub RN, Wu CO, Albitar M, Calvo KR, Young NS, Dunbar CE
Blood Adv 2020 4(8): 1700-1710 Apr 28
Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease
Hourigan CS, Dillon LW, Gui G, Logan BR, Fei M, Ghannam J, Li Y, Licon A, Alyea EP, Bashey A, Deeg HJ, Devine SM, Fernandez HF, Giralt S, Hamadani M, Howard A, Maziarz RT, Porter DL, Scott BL, Warlick ED, Pasquini MC, Horwitz ME
J Clin Oncol 2020 38(12): 1273-1283 Apr 20
Baseline TP53 mutations in adults with SCD developing myeloid malignancy following hematopoietic cell transplantation
Ghannam JY, Xu X, Maric I, Dillon L, Li Y, Hsieh MM, Hourigan CS, Fitzhugh CD
Blood 2020 135(14): 1185-1188 Apr 2
Serum microRNA profiles among dioxin exposed veterans with monoclonal gammopathy of undetermined significance
Wang W, Shim YK, Michalek JE, Barber E, Saleh LM, Choi BY, Wang CP, Ketchum N, Costello R, Marti GE, Vogt RF, Landgren O, Calvo KR
J Toxicol Environ Health A 2020 83(7): 269-278 Apr 2
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
de Jesus AA, Hou Y, Brooks S, Malle L, Biancotto A, Huang Y, Calvo KR, Marrero B, Moir S, Oler AJ, Deng Z, Montealegre Sanchez GA, Ahmed A, Allenspach E, Arabshahi B, Behrens E, Benseler S, Bezrodnik L, Bout-Tabaku S, Brescia AC, Brown D, Burnham JM, Caldirola MS, Carrasco R, Chan AY, Cimaz R, Dancey P, Dare J, DeGuzman M, Dimitriades V, Ferguson I, Ferguson P, Finn L, Gattorno M, Grom AA, Hanson EP, Hashkes PJ, Hedrich CM, Herzog R, Horneff G, Jerath R, Kessler E, Kim H, Kingsbury DJ, Laxer RM, Lee PY, Lee-Kirsch MA, Lewandowski L, Li S, Lilleby V, Mammadova V, Moorthy LN, Nasrullayeva G, O'Neil KM, Onel K, Ozen S, Pan N, Pillet P, Piotto DG, Punaro MG, Reiff A, Reinhardt A, Rider LG, Rivas-Chacon R, Ronis T, Rosen-Wolff A, Roth J, Ruth NM, Rygg M, Schmeling H, Schulert G, Scott C, Seminario G, Shulman A, Sivaraman V, Son MB, Stepanovskiy Y, Stringer E, Taber S, Terreri MT, Tifft C, Torgerson T, Tosi L, Van Royen-Kerkhof A, Wampler Muskardin T, Canna SW, Goldbach-Mansky R
J Clin Invest 2020 130(4): 1669-1682 Apr 1
Predisposition to hematologic malignancies in patients with xeroderma pigmentosum
Oetjen KA, Levoska MA, Tamura D, Ito S, Douglas D, Khan SG, Calvo KR, Kraemer KH, DiGiovanna JJ
Haematologica 2020 105(4): e144-e146 Apr
Differential processing of high-molecular-weight kininogen during normal pregnancy
Droll SH, Hsu YS, Drake SK, Kim A, Wang W, Calvo KR, Cao Z, Hu TY, Zhao Z
Rapid Commun Mass Spectrom 2020 34 Suppl 1(Suppl 1): e8552 Apr
Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update
Clara JA, Monge C, Yang Y, Takebe N
Nat Rev Clin Oncol 2020 17(4): 204-232 Apr
Timed sequential salvage chemotherapy for relapsed or refractory acute myeloid leukemia
Popescu B, Sheela S, Thompson J, Grasmeder S, Intrater T, DeStefano CB, Hourigan CS, Lai C
Clin Hematol Int 2020 2(1): 27-31 Mar
Intrahepatic cholangiocarcinoma as a rare secondary malignancy after allogeneic hematopoietic stem cell transplantation for childhood acute lymphoblastic leukemia: A case report
Good ML, Malekzadeh P, Kriley IR, Shah NN, Kleiner DE, Calvo K, Hernandez JM, Davis JL
Pediatr Transplant 2020 24(2): e13653 May
Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia
Celik H, Lindblad KE, Popescu B, Gui G, Goswami M, Valdez J, DeStefano C, Lai C, Thompson J, Ghannam JY, Fantoni G, Biancotto A, Candia J, Cheung F, Sukumar G, Dalgard CL, Smith RH, Larochelle A, Dillon LW, Hourigan CS
Blood Adv 2020 4(2): 367-379 Jan 28
Refined National Institutes of Health response algorithm for chronic graft-versus-host disease in joints and fascia
Inamoto Y, Lee SJ, Onstad LE, Flowers MED, Hamilton BK, Jagasia MH, Martin PJ, Pavletic SZ, Pidala JA, Pusic I, Vogelsang GB, Wolff D, Carpenter PA
Blood Adv 2020 4(1): 40-46 Jan 14
Next-generation sequencing for measurable residual disease detection in acute myeloid leukaemia
Ghannam J, Dillon LW, Hourigan CS
Br J Haematol 2020 188(1): 77-85 Jan
Autoimmunity Following Allogeneic Hematopoietic Stem Cell Transplantation
Buxbaum NP, Pavletic SZ
Front Immunol 2020 11(2017)
A review of mechanisms of resistance to immune checkpoint inhibitors and potential strategies for therapy
Fujiwara Y, Mittra A, Naqash AR, Takebe N
Cancer Drug Resist 2020 3(3): 252-275