Breadcrumb

Joel P. Schneider

Joel P. Schneider, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute

RESEARCH SUMMARY

The Schneider group designs and characterizes novel materials for use in drug delivery, the delivery of cells, and antibacterial therapy.

Areas of Expertise

Soft Materials
Drug Delivery
Self-Assembly
Cell Penetrating Peptides
Peptide Design, Synthesis and Characterization

Publications

Selected Key Publications

Surface-fill Hydrogel Attenuates the Oncogenic Signature of Complex Anatomical Surface Cancer in a Single Application

Poulami Majumder, Anand Singh, Ziqiu Wang, Kingshuk Dutta, Caroline Andrews, Nimit L. Patel, Junfeng Shi, Natalia de Val, Scott T. R. Walsh, Chuong D. Hoang, Joel P. Schneider
Nature Nanotechnology. DOI: 10.1038/s41565-021-00961-w: 2021.
Full-Text Article
[ Journal Article ]

Antibacterial gel coatings inspired by the cryptic function of a mussel byssal peptide

Galit Fichman, Caroline Andrews, Nimit Patel, and Joel Schneider
Advanced Materials. 33: e2103677, 2021.
Full-Text Article
[ Journal Article ]

Uncoupling the folding-function paradigm of lytic peptides to deliver impermeable inhibitors of intracellular protein-protein interactions

Stephen E. Miller, Kohei Tsuji, Terrance R. Burke Jr., and Joel P. Schneider
Journal of the American Chemical Society. 142: 19950, 2020.
Full-Text Article
[ Journal Article ]

Multiphase assembly of small molecule microcrystalline peptide hydrogel allows immunomodulatory combination therapy for long-term heart transplant survival

Poulami Majumder, Yichuan Zhang, Marcos Iglesias, Lixin Fan, James A. Kelley, Caroline Andrews, Nimit Patel, Jason R. Stagno, Byoung Chol Oh, Georg Furtmueller, Yun-Xing Wang, Gerald Brandacher, Giorgio Raimondi, Joel P. Schneider
Small. 16: e2002791, 2020.
Full-Text Article
[ Journal Article ]

De novo design of selective membrane-active peptides via enzymatic control of their conformational bias on the cell surface

Junfeng Shi and Joel P. Schneider
Angewandte Chemie International Edition. 131: 13844, 2019.
Full-Text Article
[ Journal Article ]

Job Vacancies

We have no open positions in our group at this time, please check back later.

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Team

Anderson
Postdoctoral Fellow
Caleb Anderson, Ph.D.
Tania
Postdoctoral Fellow
Tania Lopez-Silva, Ph.D.
Nambiar
Postdoctoral Fellow
Monessha Nambiar, Ph.D.
Postdoctoral Fellow
Tuan Samdin, Ph.D.
Sarkar
Postdoctoral Fellow
Srijani Sarkar, Ph.D.
Stanford
Postdoctoral Fellow
Kevon Stanford, Ph.D.

News

Image
Vincent du Vigneaud

Joel Schneider awarded the 2021 American Peptide Society Vincent du Vigneaud Award.  Vincent du Vigneaud (May 18, 1901 – December 11, 1978) was an American biochemist who won the 1955 Nobel Prize in Chemistry “for his work on biochemically important sulphur compounds, especially for the first synthesis of a polypeptide hormone,” a reference to his work on the cyclic peptide oxytocin.  The Vincent du Vigneaud Awards recognize outstanding achievement in peptide research at mid-career. The du Vigneaud Awards are sponsored by Bachem, and are awarded to two deserving recipients at the biennial American Peptide Symposia. Link to https://www.americanpeptidesociety.org/duvigneaud-award/

Image
Mesothelioma Hydrogel

Cancers that grow on the surfaces of organs and the linings of body cavities are notoriously difficult to treat. A new therapeutic hydrogel that can be injected or sprayed onto large surfaces could be an effective tool in fighting such cancers (Nat. Nanotechnol. 2021, DOI: 10.1038/s41565-021-00961-w).

Alumni

Galit Fichman, Ph.D.
Galit Fichman, Ph.D.
Postdoctoral Fellow, 2015-2021
(Assistant Professor, Hebrew University of Jerusalem)
Steve Miller, Ph.D.
Steve Miller, Ph.D.
Postdoctoral Fellow, 2014-2020
(Senior Scientist, Genentech)
Chen Liang, Ph.D.
Chen Liang, Ph.D.
Postdoctoral Fellow, 2018-2020
(Staff Scientist, Hunan University, China)
Junfeng Shi, Ph.D.
Junfeng Shi, Ph.D.
Postdoctoral Fellow, 2015-2019
(Assistant Professor, Hunan University, China)
Poulami Majumder
Poulami Majumder
Postdoctoral Fellow, 2015-2019
(Research Scientist, Eli Lilly)
Yuji Yamada, Ph.D.
Yuji Yamada, Ph.D.
Postdoctoral Fellow, 2013-2018
(Assistant Professor, Tokyo University of Pharmacy and Life Sciences, Japan)
Ken Ishikawa
Ken Ishikawa
Postdoctoral Fellow, 2016-2018
(Assistant Professor, Kurme University, Japan)
Allix Sanders, Ph.D.
Allix Sanders, Ph.D.
Postdoctoral Fellow, 2015-2018
(Kite Pharmaceuticals)
Scott Medina, Ph.D.
Scott Medina, Ph.D.
Postdoctoral Fellow, 2012-2016
(Assistant Professor, Pennsylvania State University)
Steven Tau
Steven Tau
Post Baccalaureate, 2015-2016
(MD/Ph.D. Candidate, Dartmouth College)
Katelyn Nagy-Smith, Ph.D.
Katelyn Nagy-Smith, Ph.D.
Graduate Student, 2009-2015
(Research Scientist, Merck)
Cem Sonmez, Ph.D.
Cem Sonmez, Ph.D.
Graduate Student, 2008-2014
(Postdoctoral Fellow, NCI)
Dan Smith, Ph.D.
Dan Smith, Ph.D.
Graduate Student, 2007-2013
(Scientist, GlaxoSmithKline)
Mike Giano, Ph.D.
Mike Giano, Ph.D.
Graduate Student, 2007-2013
(Postdoctoral fellow, Johnson and Johnson)
Gaia Bisaccioni, Ph.D.
Gaia Bisaccioni, Ph.D.
Graduate Student, 2013
(Fellow, School of Pharmacy, University of Bologna, Italy)
Chomdao Sinthuvanich, Ph.D.
Chomdao Sinthuvanich, Ph.D.
Graduate Student, 2006-2012
(Lecturer, Kasetsart University, Thailand)
Monica Branco, Ph.D.
Monica Branco, Ph.D.
Postdoctoral Fellow, 2009-2011
(Research Scientist, GlaxoSmithKline)
Salome Veiga, Ph.D.
Salome Veiga, Ph.D.
Postdoctoral Fellow, 2009-2011
(Staff Scientist, University of Lisbon, Portugal)
Iris Geisler, Ph.D.
Iris Geisler, Ph.D.
Postdoctoral Fellow, 2010-2011
(Research Scientist, Abbott)
Kevin Harlen
Kevin Harlen
Post Baccalaureate, 2010-2011
(Ph.D. Candidate, Harvard University)
Radhika Nagarkar, Ph.D.
Radhika Nagarkar, Ph.D.
Graduate Student, 2004-2009
(Investigator, GlaxoSmithKline)
Ronak Rughani, Ph.D.
Ronak Rughani, Ph.D.
Graduate Student, 2003-2009
(Investigator, L'Oreal)
Lisa Haines-Butterick, Ph.D.
Lisa Haines-Butterick, Ph.D.
Graduate Student, 2002-2008
(Principal Investigator, DuPont Central Research)
Daphne Salick, Ph.D.
Daphne Salick, Ph.D.
Graduate Student, 2003-2008
(Investigator, Johnson & Johnson)
Chris Micklitsch, Ph.D.
Chris Micklitsch, Ph.D.
Graduate Student, 2001-2007
(Scientist, Wellstat Diagnostics)
Karthikan Rajagopal, Ph. D.
Karthikan Rajagopal, Ph. D.
Graduate Student, 2001-2006
(Principal Investigator, Genentech)
Thomas Daniel, M.A.
Thomas Daniel, M.A.
Graduate Student, 2003-2005
Research Assistant, DuPont Company
Daniel Cline, Ph.D.
Daniel Cline, Ph.D.
Graduate Student, 1999-2005
(Un. North Carolina-Chapel Hill, Postdoctoral Fellow)
Julianna Kretsinger, Ph.D.
Julianna Kretsinger, Ph.D.
Graduate Student, 1999-2004
(Principal Investigator, Eli Lilly)
Kyung Lee, M.Sc.
Kyung Lee, M.Sc.
Graduate Student, 2001-2004
(Chemistry Teacher, Methacton High School, PA)
Mark Powell, M.Sc.
Mark Powell, M.Sc.
Graduate Student, 1999-2003
(Research Associate, Astra Zeneca Pharmaceuticals)
Sowmya Subramanian, M.Sc.
Sowmya Subramanian, M.Sc.
Graduate Student, 2000-2003
(Research Assistant, University of Delaware Composites Center)
Qian Yu, Ph.D.
Qian Yu, Ph.D.
Postdoctoral Fellow, 2001-2002
(Research Scientist, Johnson & Johnson)
Uzma Rias, Ph.D.
Uzma Rias, Ph.D.
Postdoctoral Fellow, 2000-2001
(Research Scientist, Buffalo Medical School)