Nadim Majdalani, Ph.D.

Nadim Majdalani, Ph.D.
Staff Scientist
Laboratory of Molecular Biology

Team Member of:

Susan Gottesman, Ph.D.

The lab is focused on the role that small trans-acting RNAs do in helping the bacterium E. coli respond to stresses or changes in its environment. In particular, we have been interested in the physiological conditions under which the small RNAs become expressed and what mRNAs they target.

Areas of Expertise

RNA

Contact Info

Nadim Majdalani, Ph.D.
Center for Cancer Research
National Cancer Institute
Bldg.37, Room 5132
Bethesda, MD 20892-4264
Ph: 301-451-8788
nadim@nih.gov

The lab is focused on the role that small trans-acting RNAs do in helping the bacterium E. coli respond to stresses or changes in its environment. In particular, we have been interested in the physiological conditions under which the small RNAs become expressed and what mRNAs they target.

Selected Publications

  1. Reducing acetate excretion from E. coli K-12 by over-expressing the small RNA SgrS.
    Negrete A, Majdalani N, Phue JN, Shiloach J.
    N Biotechnol. 30: 269-73, 2013. [ Journal Article ]
  2. Adenovirus with hexon Tat-protein transduction domain modification exhibits increased therapeutic effect in experimental neuroblastoma and neuroendocrine tumors.
    Yu D, Jin C, Leja J, Majdalani N, Nilsson B, Eriksson F, Essand M.
    J. Virol.. 85: 13114-23, 2011. [ Journal Article ]
  3. H-NS regulation of IraD and IraM antiadaptors for control of RpoS degradation.
    Battesti A, Tsegaye YM, Packer DG, Majdalani N, Gottesman S.
    J. Bacteriol.. 194: 2470-8, 2012. [ Journal Article ]
  4. The RpoS-mediated general stress response in Escherichia coli.
    Battesti A, Majdalani N, Gottesman S.
    Annu. Rev. Microbiol.. 65: 189-213, 2011. [ Journal Article ]
  5. Production of recombinant protein by a novel oxygen-induced system in Escherichia coli.
    Baez A, Majdalani N, Shiloach J.
    Microb. Cell Fact.. 13: 50, 2014. [ Journal Article ]

Lebanese-born, I did my undergraduate work in Biology at the American University of Beirut, Lebanon before moving to Texas A&M university where I received my PhD in Microbiology. I was first a post-doc and research fellow with Susan Gottesman at NIH before becoming the staff scientist in her lab.